Radostina A I
Arkh Anat Gistol Embriol. 1988 Aug;95(8):61-7.
By means of the planimetry and stereometry methods ultrastructural peculiarities of macrophages in the developing dermis++ and in the focus of a subacute experimental inflammation have been investigated. Quantitative characteristics of various types of macrophages are presented. The part of macrophages of various types changes depending on age of the animal or on time of the experimental inflammation. Presence of a strong positive correlation between development of the lysosomal apparatus in ontogenesis and activity of the macrophage surface is stated. In the inflammatory focus this correlation is disturbed and sometimes it changes into a negative one. During the differentiation process of macrophages the synthesis and differentiation apparatuses are the first to form and then lysosomes. It is connected with the fact that the synthesis and secretion apparatuses are necessary for lysosomal formation, as well as for secretory function of macrophages.
借助于平面测量法和立体测量法，对发育中的真皮以及亚急性实验性炎症病灶中的巨噬细胞超微结构特征进行了研究。给出了各类巨噬细胞的定量特征。不同类型巨噬细胞的占比随动物年龄或实验性炎症时间而变化。研究表明，个体发育过程中溶酶体系统的发育与巨噬细胞表面活性之间存在强正相关。在炎症病灶中，这种相关性受到干扰，有时甚至变为负相关。在巨噬细胞的分化过程中，合成和分化细胞器首先形成，然后是溶酶体。这与以下事实有关，即合成和分泌细胞器对于溶酶体的形成以及巨噬细胞的分泌功能都是必需的。
