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Repositioning Natural Products in Drug Discovery.重新定位天然产物在药物发现中的作用。
Molecules. 2020 Mar 4;25(5):1154. doi: 10.3390/molecules25051154.
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Teaching an old dog new tricks: Drug discovery by repositioning natural products and their derivatives.教老狗新把戏：重新定位天然产物及其衍生物的药物发现。
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Drug repurposing: a promising tool to accelerate the drug discovery process.药物重定位：加速药物发现过程的有前途的工具。
Drug Discov Today. 2019 Oct;24(10):2076-2085. doi: 10.1016/j.drudis.2019.06.014. Epub 2019 Jun 22.
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In silico drug repositioning: what we need to know.计算机药物重定位：我们需要了解的内容。
Drug Discov Today. 2013 Feb;18(3-4):110-5. doi: 10.1016/j.drudis.2012.08.005. Epub 2012 Aug 28.
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Editorial: Strategies in the drug discovery and development for leishmaniasis: immunomodulators, natural products, synthetic compounds, and drug repositioning.社论：利什曼病药物研发策略：免疫调节剂、天然产物、合成化合物及药物重新定位
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Patent review.专利审查。
Comb Chem High Throughput Screen. 2011 May;14(4):303. doi: 10.2174/138620711795222473.
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Review of Drug Repositioning Approaches and Resources.药物重定位方法和资源综述。
Int J Biol Sci. 2018 Jul 13;14(10):1232-1244. doi: 10.7150/ijbs.24612. eCollection 2018.
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In silico repositioning of approved drugs for rare and neglected diseases.计算机模拟法重新定位已批准药物治疗罕见和被忽视的疾病。
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Drug repositioning for treatment of movement disorders: from serendipity to rational discovery strategies.药物重定位治疗运动障碍：从偶然发现到合理的发现策略。
Curr Top Med Chem. 2013;13(18):2337-63. doi: 10.2174/15680266113136660164.
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Revisiting Repurposing.重新审视重新利用
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Antibacterial Synergism of Fluoxetine and Paroxetine with Ceftriaxone, Plasmid DNA Cleavage and Repositioning.氟西汀和帕罗西汀与头孢曲松的抗菌协同作用、质粒DNA切割与重新定位
Curr Microbiol. 2025 Jul 26;82(9):411. doi: 10.1007/s00284-025-04310-1.
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Multi-level association rule mining and network pharmacology to identify the polypharmacological effects of herbal materials and compounds in traditional medicine.多层次关联规则挖掘与网络药理学用于识别传统医学中草药和化合物的多药效应。
Brief Bioinform. 2025 Jul 2;26(4). doi: 10.1093/bib/bbaf328.
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Repurposing of paroxetine and fluoxetine for their antibacterial effects against clinical isolates in Egypt.帕罗西汀和氟西汀在埃及针对临床分离株的抗菌作用的重新利用。
AIMS Microbiol. 2025 Feb 5;11(1):126-149. doi: 10.3934/microbiol.2025007. eCollection 2025.
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Plant bioactive compounds driven microRNAs (miRNAs): A potential source and novel strategy targeting gene and cancer therapeutics.植物生物活性化合物驱动的微小RNA（miRNA）：一种靶向基因和癌症治疗的潜在来源及新策略。
Noncoding RNA Res. 2024 Jun 8;9(4):1140-1158. doi: 10.1016/j.ncrna.2024.06.003. eCollection 2024 Dec.
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Cang-ai volatile oil alleviates nasal inflammation via Th1/Th2 cell imbalance regulation in a rat model of ovalbumin-induced allergic rhinitis.苍术挥发油通过调节卵清蛋白诱导的大鼠变应性鼻炎模型中的Th1/Th2细胞失衡来减轻鼻炎症。
Front Pharmacol. 2024 May 21;15:1332036. doi: 10.3389/fphar.2024.1332036. eCollection 2024.
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Trends and Applications in Computationally Driven Drug Repurposing.计算驱动的药物重定位的趋势和应用。
Int J Mol Sci. 2023 Nov 20;24(22):16511. doi: 10.3390/ijms242216511.
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Anti-Viral Activity of Bioactive Molecules of Silymarin against COVID-19 via In Silico Studies.水飞蓟素生物活性分子通过计算机模拟研究对新冠病毒的抗病毒活性
Pharmaceuticals (Basel). 2023 Oct 17;16(10):1479. doi: 10.3390/ph16101479.
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Identification of potential biological targets of oxindole scaffolds via repositioning strategies.通过重新定位策略鉴定氧化吲哚支架的潜在生物学靶点。
F1000Res. 2022 Mar 23;11. doi: 10.12688/f1000research.109017.2. eCollection 2022.
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Repositioned Natural Compounds and Nanoformulations: A Promising Combination to Counteract Cell Damage and Inflammation in Respiratory Viral Infections.重定位天然化合物和纳米制剂：一种有前途的组合，可抵抗呼吸道病毒感染中的细胞损伤和炎症。
Molecules. 2023 May 12;28(10):4045. doi: 10.3390/molecules28104045.
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Identification of Promising Drug Candidates against Prostate Cancer through Computationally-Driven Drug Repurposing.通过计算驱动的药物再利用鉴定治疗前列腺癌的有前途的候选药物。
Int J Mol Sci. 2023 Feb 5;24(4):3135. doi: 10.3390/ijms24043135.
本文引用的文献
1
Drug repurposing: progress, challenges and recommendations.药物重定位：进展、挑战和建议。
Nat Rev Drug Discov. 2019 Jan;18(1):41-58. doi: 10.1038/nrd.2018.168. Epub 2018 Oct 12.
2
On the Integration of Drug Design Methods for Drug Repurposing.论用于药物再利用的药物设计方法的整合
Front Pharmacol. 2017 May 23;8:298. doi: 10.3389/fphar.2017.00298. eCollection 2017.
3
Underexplored Opportunities for Natural Products in Drug Discovery.天然产物在药物发现中未被充分探索的机遇。
J Med Chem. 2016 Oct 27;59(20):9295-9304. doi: 10.1021/acs.jmedchem.6b00473. Epub 2016 Jul 11.
4
Natural Products as Sources of New Drugs from 1981 to 2014.1981年至2014年作为新药来源的天然产物
J Nat Prod. 2016 Mar 25;79(3):629-61. doi: 10.1021/acs.jnatprod.5b01055. Epub 2016 Feb 7.
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