Institute of Goats and Sheep Science, Nanjing Agricultural University, No. 1 Weigang, Nanjing, Jiangsu 210095, PR China.
Jiangsu Agri-animal Husbandry Vocational College, Taizhou 225300, PR China.
Meat Sci. 2020 Jun;164:108094. doi: 10.1016/j.meatsci.2020.108094. Epub 2020 Feb 25.
The aim of this study was to investigate the effect of spirulina supplementation in a high-energy (HE) diet on lipid metabolism, oxidative status and immunity in Hu lambs. The lambs were assigned to two groups receiving either a standard diet (ST) or a HE diet. Each group was divided into three subgroups: no spirulina supplementation (control), 1% spirulina supplementation, or 3% spirulina supplementation. The body fat, serum cholesterol, triacylglycerol and oxidative stress increased in lambs fed the HE diet. However, 3% spirulina supplementation in the HE diet reduced above parameters and enhanced antioxidant capacity, including increased SOD activity and T-AOC content in serum and Longissimus thoracis et lumborum (LTL). Additionally, lambs receiving 3% spirulina supplementation showed an improvement in immunity-related parameters, including increased IgG concentration in serum and red and white blood cell counts. In conclusion, 3% spirulina supplementation in HE diet ameliorated lipid metabolic disorder and oxidative stress caused by a HE diet.
本研究旨在探讨螺旋藻补充剂对高脂（HE）饮食下湖羊脂代谢、氧化状态和免疫的影响。将羔羊分为两组，分别给予标准饮食（ST）或高脂饮食（HE）。每组再分为 3 个亚组：无螺旋藻补充（对照）、1%螺旋藻补充或 3%螺旋藻补充。高脂饮食组羔羊体脂、血清胆固醇、三酰甘油和氧化应激增加。然而，HE 饮食中 3%的螺旋藻补充降低了上述参数，并增强了抗氧化能力，包括增加血清中超氧化物歧化酶（SOD）活性和总抗氧化能力（T-AOC）含量，以及胸腰椎（LTL）中的含量。此外，接受 3%螺旋藻补充的羔羊的免疫相关参数得到改善，包括血清 IgG 浓度和红细胞和白细胞计数增加。总之，HE 饮食中 3%的螺旋藻补充改善了高脂饮食引起的脂代谢紊乱和氧化应激。
