Steinbrink Julie M, Hong David K, Bergin Stephen P, Al-Rohil Rami N, Perfect John R, Maziarz Eileen K
Division of Infectious Diseases, Duke University Medical Center, Durham, NC, USA.
Karius, Inc, Redwood City, USA.
Med Mycol Case Rep. 2020 Feb 13;27:77-80. doi: 10.1016/j.mmcr.2020.02.003. eCollection 2020 Mar.
Diagnosis of invasive fungal disease remains an ongoing challenge for clinicians, while continuously evolving treatment regimens increase patient risk for invasive infection. This case highlights how molecular testing led to the diagnosis of co-infection with two fungal pathogens producing invasive disease in a hematopoietic stem cell transplant recipient with graft-versus-host disease (GVHD).
侵袭性真菌病的诊断对临床医生来说仍然是一项持续存在的挑战，而不断演变的治疗方案增加了患者发生侵袭性感染的风险。本病例突出显示了分子检测如何在一名患有移植物抗宿主病（GVHD）的造血干细胞移植受者中，促成了对两种导致侵袭性疾病的真菌病原体合并感染的诊断。
