Jansen P H, Keyser A, Raes B C
Institute of Neurology, St. Radboud Hospital, Catholic University, Nijmegen, The Netherlands.
Eur Arch Psychiatry Neurol Sci. 1988;238(1):28-30. doi: 10.1007/BF00381076.
Psychiatric manifestations of familial spastic paraplegia are rare and have been described only infrequently. A 35-year-old male is reported, who presented both hypomanic behaviour and gait disturbances as features of a previously undiagnosed familial spastic paraplegia. This association implies that the CNS manifestations of familial spastic paraplegia may overlap with the neurochemical or neuroanatomic substrata regulating mood.
