Thambiah Subashini C, Yeap Swan Sim
Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, 43400 UPM, Selangor, Malaysia.
Department of Medicine, Subang Jaya Medical Centre, 47500 Subang Jaya, Selangor, Malaysia.
Clin Biochem Rev. 2020 Feb;41(1):29-40. doi: 10.33176/AACB-19-00034.
Osteoporosis (OP) is a condition where there is low bone density and microarchitectural deterioration which can predispose to fragility fractures. There is a wealth of literature on OP from the developed countries, but less so from Asia. This review will explore the field of OP research in South-East Asia with regard to the epidemiology, the diagnosis of OP and the role of laboratory tests in the management of OP, with emphasis on 25-dihydroxyvitamin D and bone turnover markers.
骨质疏松症(OP)是一种骨密度降低且微结构恶化的病症,可导致脆性骨折。发达国家有大量关于OP的文献,但亚洲的相关文献较少。本综述将探讨东南亚地区OP研究领域中关于流行病学、OP的诊断以及实验室检测在OP管理中的作用,重点关注25-二羟基维生素D和骨转换标志物。