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亚洲髋部骨折最新预测:亚洲骨质疏松症协会联合会研究

An updated hip fracture projection in Asia: The Asian Federation of Osteoporosis Societies study.

作者信息

Cheung Ching-Lung, Ang Seng Bin, Chadha Manoj, Chow Eddie Siu-Lun, Chung Yoon-Sok, Hew Fen Lee, Jaisamrarn Unnop, Ng Hou, Takeuchi Yasuhiro, Wu Chih-Hsing, Xia Weibo, Yu Julie, Fujiwara Saeko

机构信息

Department of Pharmacology and Pharmacy, Centre for Genomic Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China.

The Osteoporosis Society of Hong Kong, Hong Kong, China.

出版信息

Osteoporos Sarcopenia. 2018 Mar;4(1):16-21. doi: 10.1016/j.afos.2018.03.003. Epub 2018 Mar 22.

Abstract

OBJECTIVES

Hip fracture is a major public health problem. Earlier studies projected that the total number of hip fracture will increase dramatically by 2050, and most of the hip fracture will occur in Asia. To date, only a few studies provided the updated projection, and none of them focused on the hip fracture projection in Asia. Thus, it is essential to provide the most up to date prediction of hip fracture in Asia, and to evaluate the total direct medical cost of hip fracture in Asia.

METHODS

We provide the updated projection of hip fracture in 9 Asian Federation of Osteoporosis Societies members using the most updated incidence rate and projected population size.

RESULTS

We show that the number of hip fracture will increase from 1,124,060 in 2018 to 2,563,488 in 2050, a 2.28-fold increase. This increase is mainly due to the changes on the population demographics, especially in China and India, which have the largest population size. The direct cost of hip fracture will increase from 9.5 billion United State dollar (USD) in 2018 to 15 billion USD in 2050, resulting a 1.59-fold increase. A 2%-3% decrease in incidence rate of hip fracture annually is required to keep the total number of hip fracture constant over time.

CONCLUSIONS

The results show that hip fracture remains a key public health issue in Asia, despite the available of better diagnosis, treatment, and prevention of fracture over the recent years. Healthcare policy in Asia should be aimed to reduce the burden of hip fracture.

摘要

目的

髋部骨折是一个重大的公共卫生问题。早期研究预测,到2050年髋部骨折总数将急剧增加,且大多数髋部骨折将发生在亚洲。迄今为止,只有少数研究提供了最新预测,且没有一项研究聚焦于亚洲的髋部骨折预测。因此,提供亚洲髋部骨折的最新预测并评估亚洲髋部骨折的直接医疗总成本至关重要。

方法

我们使用最新发病率和预计人口规模,对亚洲骨质疏松症协会联合会的9个成员国的髋部骨折情况进行了最新预测。

结果

我们发现,髋部骨折数量将从2018年的1,124,060例增加到2050年的2,563,488例,增长2.28倍。这种增长主要归因于人口结构的变化,尤其是在中国和印度,这两个国家人口最多。髋部骨折的直接成本将从2018年的95亿美元增加到2050年的150亿美元,增长1.59倍。若要使髋部骨折总数随时间保持不变,每年髋部骨折发病率需降低2%-3%。

结论

结果表明,尽管近年来在骨折的诊断、治疗和预防方面有了更好的方法,但髋部骨折仍是亚洲的一个关键公共卫生问题。亚洲的医疗政策应旨在减轻髋部骨折的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01b5/6362950/ee75ecf8f785/gr1.jpg

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