腰果对血脂的影响：系统评价和荟萃分析。

Effect of Cashew Nut on Lipid Profile: A Systematic Review and Meta-Analysis.

机构信息

Department of Nutritional Science, School of Nutritional Science and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Department of Biostatistics and Epidemiology, School of Public Health, Babol University of Medical Sciences, Babol, Iran.

出版信息

Complement Med Res. 2020;27(5):348-356. doi: 10.1159/000506348. Epub 2020 Mar 11.

DOI:10.1159/000506348

PMID:32160624

Abstract

INTRODUCTION

Nuts are one of the dietary components which appear to have beneficial effects on cardiovascular disease biomarkers. Studies demonstrate beneficial effects of cash-ews on serum lipids concentration, but results in the literature remain inconclusive. We conducted a review to examine the effects of cashew nut supplementation on serum lipid profile.

METHODS

Two reviewers independently searched PubMed, Web of Science, Cochrane Library, Scopus, and EMBASE electronic databases from inception until June 2019 without language limitation. Random- and fixed-effects models were used to calculate 95% confidence intervals (CI) for studies.

RESULTS

Six randomized clinical trials comprising 531 participants were included in this systematic review. Three studies were included in the meta-analysis model. There were no significant changes for total cholesterol (TC) (standardized mean difference [SMD]: -0.02, 95% CI: -0.32, 0.28), triglycerides (TG) (SMD: -0.01, 95% CI: -0.22, 0.20), high-density lipoprotein (HDL) cholesterol (SMD: 0.09, 95% CI: -0.16, 0.34), or low-density lipoprotein (LDL) cholesterol (SMD: -0.18, 95% CI: -0.75, 0.39).

CONCLUSION

The results of this analysis demonstrate that treatment with cashew nut supplementation alone did not significantly change serum levels of LDL, HDL, TC, or TG.

摘要

简介

坚果是对心血管疾病生物标志物具有有益影响的饮食成分之一。研究表明，腰果对血清脂质浓度有有益影响，但文献中的结果仍不确定。我们进行了一项综述，以检查腰果补充剂对血清脂质谱的影响。

方法

两位审阅者独立搜索了 PubMed、Web of Science、Cochrane Library、Scopus 和 EMBASE 电子数据库，检索时间从建库开始至 2019 年 6 月，不限制语言。使用随机和固定效应模型计算研究的 95%置信区间 (CI)。

结果

本次系统评价共纳入 6 项随机临床试验，共 531 名参与者。有 3 项研究纳入了荟萃分析模型。总胆固醇（TC）（标准化均数差 [SMD]：-0.02，95%CI：-0.32，0.28）、甘油三酯（TG）（SMD：-0.01，95%CI：-0.22，0.20）、高密度脂蛋白（HDL）胆固醇（SMD：0.09，95%CI：-0.16，0.34）或低密度脂蛋白（LDL）胆固醇（SMD：-0.18，95%CI：-0.75，0.39）均无显著变化。