School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, P. R. China.
Am J Chin Med. 2020;48(2):287-328. doi: 10.1142/S0192415X20500159. Epub 2020 Mar 11.
Flacourtiaceae plants are widely used as folk medicines in traditional medicine systems for its chemical diversity and pharmacological activities. In many different areas, Flacourtiaceae plants are used as traditional medicines for the treatment of ulcers, malaria, rheumatism. The Flacourtiaceae plants contain a very plentiful chemical composition, and phytochemical studies show that the Flacourtiaceae plants contained terpenoids, aromatic glycosides, flavnoids, phenylpropanoids, alkaloids, fatty hydrocarbon, and other compounds. In pharmacological studies, various extract and isolated individual compounds exhibited antitumor, anti-oxidation, and anti-inflammatory activities. In this review, the literature data on the chemical constituents and pharmacological investigations of the Flacourtiaceae plants are summarized, to provide information about a more comprehensive chemical composition and detailed pharmacological activities of Flacourtiaceae plants, with a view of further development of clinical medication. However, research on quantitative analysis, toxicity, and drug safety and is still insufficient, and further research is required.
藤黄科植物因其化学多样性和药理学活性而被广泛用作传统医学中的民间药物。在许多不同的地区，藤黄科植物被用作传统药物，用于治疗溃疡、疟疾、风湿等疾病。藤黄科植物含有非常丰富的化学成分，植物化学研究表明，藤黄科植物含有萜类、芳香糖苷、类黄酮、苯丙素、生物碱、脂肪烃和其他化合物。在药理学研究中，各种提取物和分离的单个化合物表现出抗肿瘤、抗氧化和抗炎活性。在这篇综述中，总结了藤黄科植物的化学成分和药理学研究的文献数据，为藤黄科植物更全面的化学成分和详细的药理学活性提供了信息，以期进一步开发临床药物。然而，关于定量分析、毒性和药物安全性的研究仍然不足，需要进一步研究。
