David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Department of Medicine Statistics Core, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Pediatr Dermatol. 2021 Sep;38(5):1132-1136. doi: 10.1111/pde.14765. Epub 2021 Aug 31.
BACKGROUND/OBJECTIVES: Hidradenitis suppurativa (HS) is understudied in the pediatric population. Adult HS patients are known to have a high comorbidity burden. We aimed to describe physical and psychosocial comorbidities in a cohort of pediatric HS patients.
A retrospective chart review of pediatric HS patients at a single academic institution was conducted. Data on patient demographics, disease characteristics, and physical and psychosocial comorbidities in pediatric patients with HS were collected and analyzed.
Seventy-three pediatric patients were included in this study, 81% female. Mean (SD) age of HS disease onset was 12.6 (2.9) years. Comorbid conditions were reported in 68 of 73 (93%) patients. Significantly increased rates of several comorbidities were seen in our cohort as compared to the general US pediatric population. Metabolic and endocrine abnormalities were prevalent, with 52% (22/42) patients with obesity and 10% (6/59) with polycystic ovary syndrome. The most common cutaneous comorbidity was acne vulgaris, seen in 37% (27/73) of patients. Over one quarter (21/73, 29%) of patients had either an anxiety or depression disorder. Almost one-fifth (14/73, 19%) of our cohort had a diagnosis of asthma and other reactive airway diseases. Only one-third (24/73, 33%) of patients had documentation regarding impact of HS on their daily life. Overall, comorbidities largely did not significantly differ based on race, gender, or disease severity.
Pediatric patients with HS face a high-comorbidity burden, especially with psychiatric conditions. Early identification, including routine mental health screening, and management of comorbidities is warranted in the pediatric HS population.
背景/目的：化脓性汗腺炎（HS）在儿科人群中研究较少。已知成年 HS 患者的合并症负担很高。我们旨在描述儿科 HS 患者队列中的身体和心理社会合并症。
对单一学术机构的儿科 HS 患者进行回顾性图表审查。收集和分析了儿科 HS 患者的人口统计学数据、疾病特征以及身体和心理社会合并症的数据。
本研究共纳入 73 例儿科患者，其中 81%为女性。HS 发病的平均（SD）年龄为 12.6（2.9）岁。68/73（93%）例患者报告有合并症。与一般美国儿科人群相比，我们的队列中存在几种合并症的发生率显著增加。代谢和内分泌异常较为常见，肥胖患者占 52%（22/42），多囊卵巢综合征患者占 10%（6/59）。最常见的皮肤合并症是寻常痤疮，见于 37%（27/73）的患者。超过四分之一（21/73，29%）的患者患有焦虑或抑郁障碍。近五分之一（14/73，19%）的患者患有哮喘和其他呼吸道疾病。我们的队列中只有三分之一（24/73，33%）的患者有关于 HS 对其日常生活影响的记录。总体而言，合并症在很大程度上与种族、性别或疾病严重程度无关。
儿科 HS 患者面临着很高的合并症负担，尤其是与精神疾病有关。需要对儿科 HS 人群进行早期识别，包括常规心理健康筛查和合并症管理。
