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营养、健康与疾病:特定海洋和植物性营养保健品的作用。

Nutrition, Health, and Disease: Role of Selected Marine and Vegetal Nutraceuticals.

机构信息

EuroEspes Biomedical Research Center, Institute of Medical Science and Genomic Medicine, 15165-Bergondo, Corunna, Spain.

EuroEspes Biotechnology, Polígono Industrial de Bergondo, Parroquia de Guísamo, A-6, 15165-Bergondo, Corunna, Spain.

出版信息

Nutrients. 2020 Mar 11;12(3):747. doi: 10.3390/nu12030747.

Abstract

The investigation of new alternatives for disease prevention through the application of findings from dietary and food biotechnology is an ongoing challenge for the scientific community. New nutritional trends and the need to meet social and health demands have inspired the concept of functional foods and nutraceuticals which, in addition to their overall nutritional value, present certain properties for the maintenance of health. However, these effects are not universal. Nutrigenetics describes how the genetic profile has an impact on the response of the body to bioactive food components by influencing their absorption, metabolism, and site of action. The EbioSea Program, for biomarine prospection, and the Blue Butterfly Program, for the screening of vegetable-derived bioproducts, have identified a new series of nutraceuticals, devoid of side effects at conventional doses, with genotype-dependent preventive and therapeutic activity. Nutrigenomics and nutrigenetics provide the opportunity to explore the inter-individual differences in the metabolism of and response to nutrients, achieving optimal results. This fact leads to the concept of personalized nutrition as opposed to public health nutrition. Consequently, the development and prescription of nutraceuticals according to the individual genetic profile is essential to improve their effectiveness in the prevention and natural treatment of prevalent diseases.

摘要

通过应用饮食和食品生物技术的研究成果来探索新的疾病预防方法,是科学界面临的一项持续挑战。新的营养趋势和满足社会与健康需求的需要,激发了功能性食品和营养保健品的概念,这些产品除了具有整体营养价值外,还具有某些维持健康的特性。然而,这些效果并非普遍适用。营养遗传学描述了遗传特征如何通过影响生物活性食物成分的吸收、代谢和作用部位,对身体对它们的反应产生影响。EbioSea 计划(用于海洋生物勘探)和 BlueButterfly 计划(用于筛选植物来源的生物制品)已经确定了一系列新的营养保健品,这些保健品在常规剂量下没有副作用,并且具有依赖于基因型的预防和治疗作用。营养基因组学和营养遗传学为探索个体间对营养素的代谢和反应差异提供了机会,从而实现最佳效果。这一事实导致了个性化营养的概念,与公共卫生营养形成对比。因此,根据个体的遗传特征来开发和开营养保健品对于提高它们在预防和自然治疗常见疾病方面的效果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dee0/7146393/6285a863ed8e/nutrients-12-00747-g001.jpg

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