Department of Epidemiology, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands.
Department of Physiotherapy, Maastricht University Medical Center+, Maastricht, The Netherlands.
Arch Phys Med Rehabil. 2020 Aug;101(8):1288-1295. doi: 10.1016/j.apmr.2019.12.023. Epub 2020 Mar 10.
To assess the efficacy of a 12-week aquatic cycling training program for improving knee pain and physical functioning in patients with knee osteoarthritis (OA).
Two-arm, single-blind, parallel-group randomized controlled trial.
OA outpatient clinic of the Maastricht University Medical Center+.
Patients (N=111, 50-70y) with unilateral mild-to-moderate knee OA.
Participants (aquatic cycling [AC] group, n=55) received AC sessions of 45 min each 2 times per week. Each session combined upright seated cycling with out-of-saddle positions and exercises for the upper and lower body. The usual care (UC) group (n=47) continued with UC and was offered 12 AC sessions in a local swimming pool after their trial participation.
The Knee Injury and Osteoarthritis Outcome Score (KOOS) on knee pain and physical function was assessed at baseline, postintervention, and at 24-wk follow-up. Multilevel (mixed regression) analysis examined the effects.
Average attendance rate for the AC sessions was 80%. Statistically significant differences at postintervention and follow-up were found for knee pain in mean ± SD (UC pretest, 57.89±15.26; posttest, 55.90±18.04; follow-up, 57.24±19.16; and AC pretest, 56.96±12.96; posttest, 63.55±15.33; follow-up, 64.35±17.26; estimate, 8.16; SE, 3.27; 95% confidence interval [CI], 1.67-14.64; effect size [ES], 0.50) and physical functioning (UC pretest, 66.32±16.28; posttest, 66.80±19.04; follow-up, 65.42±17.98; and AC pretest, 61.89±17.151; posttest, 70.14±17.52; follow-up, 69.00±16.84; estimate, 7.16; SE, 3.19; 95% CI, 0.83-13.49; ES, 0.43) in favor of the aquatic group.
The results suggest that a 12-week AC training program improves self-reported knee pain and physical functioning in patients with mild-to-moderate knee OA compared to UC.
评估为期 12 周的水上自行车训练方案对改善膝骨关节炎（OA）患者膝关节疼痛和身体功能的疗效。
双臂、单盲、平行组随机对照试验。
马斯特里赫特大学医学中心的 OA 门诊。
单侧轻度至中度膝 OA 的患者（N=111，50-70 岁）。
参与者（水上自行车 [AC] 组，n=55）接受每次 45 分钟、每周 2 次的 AC 课程。每次课程将直立坐姿骑行与鞍外位置和上下身锻炼相结合。常规护理（UC）组（n=47）继续接受 UC，并在试验参与后在当地游泳池接受 12 次 AC 课程。
基线、干预后和 24 周随访时使用膝关节损伤和骨关节炎结果评分（KOOS）评估膝关节疼痛和身体功能。采用多水平（混合回归）分析检查效果。
AC 课程的平均出勤率为 80%。在干预后和随访时，膝关节疼痛的平均差异具有统计学意义（UC 术前，57.89±15.26；术后，55.90±18.04；随访，57.24±19.16；AC 术前，56.96±12.96；术后，63.55±15.33；随访，64.35±17.26；估计值，8.16；SE，3.27；95%置信区间 [CI]，1.67-14.64；效应量 [ES]，0.50）和身体功能（UC 术前，66.32±16.28；术后，66.80±19.04；随访，65.42±17.98；AC 术前，61.89±17.151；术后，70.14±17.52；随访，69.00±16.84；估计值，7.16；SE，3.19；95% CI，0.83-13.49；ES，0.43）有利于水上组。
与 UC 相比，12 周的水上自行车训练方案可改善轻度至中度膝 OA 患者的自我报告膝关节疼痛和身体功能。
