Wondie Yemataw, Hinz Andreas
Department of Psychology, University of Gondar, Gondar, Ethiopia.
Department of Medical Psychology and Medical Sociology, University of Leipzig, Philipp-Rosenthal-Str. 55, 04103, Leipzig, Germany.
Support Care Cancer. 2020 Nov;28(11):5469-5478. doi: 10.1007/s00520-020-05398-w. Epub 2020 Mar 13.
Cancer is of increasing prevalence in less-developed countries. However, research on the patients' quality of life (QoL) in these countries is very limited. The aim of this study was to examine QoL of cancer patients in Africa.
A sample of 256 cancer patients treated in an Ethiopian hospital was examined with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire EORTC QLQ-C30, the Multidimensional Fatigue Inventory, and the Hospital Anxiety and Depression Scale. A group of 1664 German cancer patients served as a comparison group.
Most of the scales of the EORTC QLQ-C30 showed acceptable reliability in the Ethiopian sample. Compared with the German cancer patients, the Ethiopian patients showed lower QoL in most dimensions, especially in financial difficulties, physical functioning, pain, and appetite loss (effect sizes between 0.52 and 0.75). Illiteracy, tumor stage, and treatment (surgery and chemotherapy) were associated with QoL in the Ethiopian sample. QoL was strongly correlated with fatigue, anxiety, and depression.
The EORTC QLQ-C30 is a suitable instrument for measuring QoL in Ethiopia. The detriments in QoL in the Ethiopian patients indicate specific cancer care needs for the patients in a developing country.
癌症在欠发达国家的患病率日益上升。然而,对这些国家患者生活质量(QoL)的研究非常有限。本研究的目的是调查非洲癌症患者的生活质量。
使用欧洲癌症研究与治疗组织生活质量问卷EORTC QLQ-C30、多维疲劳量表和医院焦虑抑郁量表,对在埃塞俄比亚一家医院接受治疗的256名癌症患者进行了调查。一组1664名德国癌症患者作为对照组。
EORTC QLQ-C30的大多数量表在埃塞俄比亚样本中显示出可接受的信度。与德国癌症患者相比,埃塞俄比亚患者在大多数维度上的生活质量较低,尤其是在经济困难、身体功能、疼痛和食欲丧失方面(效应大小在0.52至0.75之间)。在埃塞俄比亚样本中,文盲、肿瘤分期和治疗(手术和化疗)与生活质量相关。生活质量与疲劳、焦虑和抑郁密切相关。
EORTC QLQ-C30是测量埃塞俄比亚生活质量的合适工具。埃塞俄比亚患者生活质量的损害表明发展中国家的患者有特定的癌症护理需求。