Department of Surgery, National Center for Functional Glycomics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
Bioinformatics. 2020 Jun 1;36(11):3613-3614. doi: 10.1093/bioinformatics/btaa190.
Glycan structures are commonly represented using symbols or linear nomenclature such as that from the Consortium for Functional Glycomics (also known as modified IUPAC-condensed nomenclature). No current tool allows for writing the name in such format using a graphical user interface (GUI); thus, names are prone to errors or non-standardized representations.
Here we present GlycoGlyph, a web application built using JavaScript, which is capable of drawing glycan structures using a GUI and providing the linear nomenclature as an output or using it as an input in a dynamic manner. GlycoGlyph also allows users to save the structures as an SVG vector graphic, and allows users to export the structure as condensed GlycoCT.
The application can be used at: https://glycotoolkit.com/Tools/GlycoGlyph/. The application is tested to work in modern web browsers such as Firefox or Chrome.
聚糖结构通常使用符号或线性命名法表示,例如功能糖组学联合会(也称为改良的 IUPAC-缩合命名法)。目前没有工具可以使用图形用户界面(GUI)以这种格式编写名称;因此,名称容易出错或表示不规范。
这里我们展示了 GlycoGlyph,这是一个使用 JavaScript 构建的 Web 应用程序,它能够使用 GUI 绘制聚糖结构,并提供线性命名法作为输出,或以动态方式将其用作输入。GlycoGlyph 还允许用户将结构保存为 SVG 矢量图形,并允许用户将结构导出为缩合 GlycoCT。
该应用程序可在以下网址使用:https://glycotoolkit.com/Tools/GlycoGlyph/。该应用程序经过测试,可在 Firefox 或 Chrome 等现代 Web 浏览器中运行。