Dokuz Eylül University, Graduate School of Health Sciences, Department of Physical Therapy and Rehabilitation, İzmir, Turkey
Dokuz Eylül University, Faculty of Medicine, Department of Endocrinology and Metabolism, İzmir, Turkey
Turk J Med Sci. 2020 Jun 23;50(4):789-797. doi: 10.3906/sag-1906-63.
BACKGROUND/AIM: The aim of this study was to demonstrate the validity and reliability of the Turkish version of the Michigan Neuropathy Screening Instrument (MNSI-TR).
The study included 127 patients aged 45–76 years who were previously diagnosed with type 1 or 2 diabetes. Stability of the instrument was assessed by intraclass correlation coefficient. Reliability of the MNSI-TR was assessed using the Kuder– Richardson formula 20 test, item-total correlations, and floor/ceiling effect. Validity was evaluated with receiver operating characteristic curve analysis. A logistic regression model was used to determine to what degree the MNSI-TR explain nerve conduction study (NCS) results in the prediction of neuropathy.
With a cut-off value of 3.5 for the questionnaire, sensitivity and specificity of the MNSI-TR were 75.5% and 68.1%, respectively. A cut-off of 2.75 for the physical assessment part of the scale resulted in 87.5% sensitivity and 93.6% specificity. The scale was able to diagnose neuropathy in the rate of 71.5% of the patients diagnosed with neuropathy by NCS.
The MNSI-TR is a valid and reliable method for evaluating diabetic peripheral neuropathy in Turkish speaking societies. It must be obtained a minimum of 4 points from the questionnaire part and a minimum of 2.5 points from the physical assessment part for the diagnosis of neuropathy
背景/目的：本研究旨在验证密歇根神经病变筛查工具（MNSI-TR）土耳其语版本的有效性和可靠性。
该研究纳入了 127 名年龄在 45-76 岁之间的 1 型或 2 型糖尿病患者。采用组内相关系数评估仪器的稳定性。采用 Kuder–Richardson 公式 20 检验、条目-总分相关性以及地板/天花板效应评估 MNSI-TR 的可靠性。采用受试者工作特征曲线分析评估有效性。使用逻辑回归模型确定 MNSI-TR 在多大程度上能够解释神经传导研究（NCS）结果，从而预测神经病变。
问卷的截断值为 3.5 时，MNSI-TR 的敏感性和特异性分别为 75.5%和 68.1%。量表体格检查部分的截断值为 2.75 时，敏感性为 87.5%，特异性为 93.6%。该量表能够以 71.5%的比率诊断出通过 NCS 诊断为神经病变的患者中的神经病变。
MNSI-TR 是一种在土耳其语人群中评估糖尿病周围神经病变的有效且可靠的方法。问卷部分至少要获得 4 分，体格检查部分至少要获得 2.5 分才能诊断为神经病变。
