Jiang Xue, Meng Weiqi, Li Lanzhou, Meng Zhaoli, Wang Di
Department of Translational Medicine Research Institute, First Hospital, Jilin University, Changchun, China.
School of Life Sciences, Jilin University, Changchun, China.
Front Pharmacol. 2020 Feb 28;11:168. doi: 10.3389/fphar.2020.00168. eCollection 2020.
Diabetic complications seriously endanger the health of most diabetic patients around the world. Most chemical hypoglycemic agents have adverse effects and are unable to improve the progression of diabetic complications. In recent years, a number of medicinal herbs have become increasingly popular for the treatment of diabetic complications due to their relative safety. Polysaccharides extracted from medicinal herbs with multiple pharmacological activities and low toxicity have been reported to be useful in the treatment of diabetic complications.
Primary studies with keywords including polysaccharide and diabetic complications were retrieved from the Web of Science and NCBI databases and were read and analyzed.
Mushroom polysaccharides were proven to have positive effects on diabetic complications.
We studied the effects of mushroom polysaccharides on hyperglycemia and as adjuvant therapies for diabetic complications and summarized the applications and limitations of mushroom polysaccharides to better understand their application for the treatment of diabetic complications.
糖尿病并发症严重威胁着全球大多数糖尿病患者的健康。大多数化学降糖药物都有不良反应，且无法改善糖尿病并发症的进展。近年来，一些草药因其相对安全性，在治疗糖尿病并发症方面越来越受欢迎。据报道，从具有多种药理活性和低毒性的草药中提取的多糖可用于治疗糖尿病并发症。
从科学网和NCBI数据库中检索关键词包括多糖和糖尿病并发症的初步研究，并进行阅读和分析。
蘑菇多糖被证明对糖尿病并发症有积极作用。
我们研究了蘑菇多糖对高血糖的影响以及作为糖尿病并发症辅助治疗的作用，并总结了蘑菇多糖的应用和局限性，以便更好地了解它们在治疗糖尿病并发症中的应用。
