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欧洲野生动物谱系的分子流行病学:综述

Molecular Epidemiology of Lineages in Wild Animals in Europe: A Review.

作者信息

Silva Vanessa, Capelo José L, Igrejas Gilberto, Poeta Patrícia

机构信息

Microbiology and Antibiotic Resistance Team (MicroART), Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro (UTAD), 5000-801 Vila Real, Portugal.

Department of Genetics and Biotechnology, University of Trás-os-Montes and Alto Douro (UTAD), 5000-801 Vila Real, Portugal.

出版信息

Antibiotics (Basel). 2020 Mar 14;9(3):122. doi: 10.3390/antibiotics9030122.

Abstract

is an opportunist pathogen that is responsible for numerous types of infections. is known for its ability to easily acquire antibiotic resistance determinants. Methicillin-resistant (MRSA) is a leading cause of infections both in humans and animals and is usually associated with a multidrug-resistant profile. MRSA dissemination is increasing due to its capability of establishing new reservoirs and has been found in humans, animals and the environment. Despite the fact that the information on the incidence of MRSA in the environment and, in particular, in wild animals, is scarce, some studies have reported the presence of these strains among wildlife with no direct contact with antibiotics. This shows a possible transmission between species and, consequently, a public health concern. The aim of this review is to better understand the distribution, prevalence and molecular lineages of MRSA in European free-living animals.

摘要

是一种机会致病菌,可引发多种类型的感染。以其易于获得抗生素耐药决定因素的能力而闻名。耐甲氧西林金黄色葡萄球菌(MRSA)是人类和动物感染的主要原因,通常与多重耐药谱相关。由于其能够建立新的储存宿主,MRSA的传播正在增加,并且已在人类、动物和环境中被发现。尽管关于环境中,特别是野生动物中MRSA发病率的信息很少,但一些研究报告称在未直接接触抗生素的野生动物中存在这些菌株。这表明可能存在物种间传播,因此引发了公共卫生问题。本综述的目的是更好地了解欧洲自由生活动物中MRSA的分布、流行情况和分子谱系。

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