Rantala M L
Department II of Obstetrics and Gynaecology, Helsinki University Central Hospital, Finland.
Acta Obstet Gynecol Scand. 1988;67(5):429-32. doi: 10.3109/00016348809004254.
The etiology of infertility was evaluated in 98 previously unexamined couples at Helsinki University Central Hospital. Female endocrine disturbances (33%) and male causes (26%) were the most common factors of infertility. Two or more causes were found in 28 couples (29%). Both female and male factors were involved in 8% of cases. Eighteen of 98 women became pregnant during the infertility evaluation before any treatment was given. At four years the cumulative pregnancy rates were 65% for all couples and 60% and 51% for couples with single-factor and multifactorial infertility, respectively. The mean age was significantly higher (p less than 0.05) among those who failed to conceive than among those who conceived. Ovulatory disturbances and multiple causes are common factors in reproductive failure, but even in the presence of multifactorial infertility the primary referrals have good chances of achieving pregnancy.
在赫尔辛基大学中心医院，对98对之前未接受过检查的夫妇的不孕病因进行了评估。女性内分泌紊乱（33%）和男性因素（26%）是最常见的不孕因素。在28对夫妇（29%）中发现了两种或更多病因。8%的病例中同时涉及女性和男性因素。98名女性中有18名在不孕评估期间、未接受任何治疗前就怀孕了。四年时，所有夫妇的累积妊娠率为65%，单因素不孕夫妇和多因素不孕夫妇的累积妊娠率分别为60%和51%。未受孕者的平均年龄显著高于受孕者（p<0.05）。排卵障碍和多种病因是生殖失败的常见因素，但即使存在多因素不孕，初诊患者仍有很大机会实现妊娠。
