Emerg Infect Dis. 2020 Apr;26(4):692-699. doi: 10.3201/eid2604.191011.
We conducted an epidemiologic study of severe fever with thrombocytopenia syndrome (SFTS) in Japan during 2013-2017. Of 303 cases reported during that period, 133 (44%) were included in this study. The median time between onset of illness and diagnosis of SFTS shortened, from 11.5 to 3.0 days, but the case-fatality rate remained high, at 27%. In 64 patients (48%), a close contact with companion animals was reported within 2 weeks of disease onset. Of these 64 patients, 40 were surveyed further, and we confirmed that 3 had direct contact with body fluids of ill companion animals; 2 had direct contact with the saliva of an ill feral cat or pet dog. These patients reported no history of tick bite, suggesting that ill companion animals might be a source of SFTS virus transmission. Direct contact with the body fluids of ill companion animals should be avoided.
我们对 2013-2017 年期间在日本发生的严重发热伴血小板减少综合征（SFTS）进行了一项流行病学研究。在此期间报告的 303 例病例中，有 133 例（44%）被纳入本研究。SFTS 的发病至诊断的中位时间缩短，从 11.5 天缩短至 3.0 天，但病死率仍很高，为 27%。在 64 例患者（48%）中，报告在发病后 2 周内与伴生动物有密切接触。在这 64 例患者中，进一步调查了 40 例，我们确认其中 3 例与患病伴生动物的体液有直接接触；2 例与患病野猫或宠物狗的唾液有直接接触。这些患者没有蜱虫叮咬史，提示患病伴生动物可能是 SFTS 病毒传播的来源。应避免与患病伴生动物的体液直接接触。
