Panisello J M, Martinez-Vea A, Garcia C, Carrera M, Oliver J A, Richart C
Section of Nephrology, Hospital Juan XXIII, Tarragona, Spain.
Am J Nephrol. 1988;8(6):477-8. doi: 10.1159/000167662.
We report a patient with polycystic kidney disease, advanced renal failure, and nephrotic-range proteinuria. Kidney biopsy revealed IgA nephropathy with lesions of focal and segmental glomerular sclerosis. This association had not been previously described and is probably coincidental. This case supports the assumption that the nephrotic-range proteinuria observed in some polycystic patients could be the consequence of another superimposed glomerular disease. This glomerulopathy can worsen the course of azotemia in these patients.
我们报告了一名患有多囊肾病、晚期肾衰竭和肾病范围蛋白尿的患者。肾脏活检显示为IgA肾病合并局灶节段性肾小球硬化病变。这种关联以前未曾有过描述，可能是巧合。该病例支持了这样一种假设，即一些多囊肾患者中观察到的肾病范围蛋白尿可能是另一种叠加性肾小球疾病的结果。这种肾小球病会使这些患者的氮质血症病程恶化。
