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人体吸入暴露于气溶胶和健康影响:气溶胶监测和建模区域沉积剂量。

Human Inhalation Exposure to Aerosol and Health Effect: Aerosol Monitoring and Modelling Regional Deposited Doses.

机构信息

Department of Health & Environmental Science, Korea University, Seoul 02841, Korea.

Department of Materials Science and Engineering, Kumoh National Institute of Technology, 61 Daehak-ro (yangho-dong), Gumi, Gyeongbuk 39177, Korea.

出版信息

Int J Environ Res Public Health. 2020 Mar 16;17(6):1923. doi: 10.3390/ijerph17061923.

DOI:10.3390/ijerph17061923
PMID:32187987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7142517/
Abstract

Since poor air quality affects human health in the short and long term, much research has been performed on indoor and outdoor aerosol exposure; however, there is a lack of specific data on the exposure and health risks of inhalable aerosols that contain bioaerosol in different environments of human life. To investigate the potential exposure to inhalable aerosols (in the monitoring of particulate matter (PM) based on R modeling, variations of PM depend on the ventilation system and bioaerosols based on size distribution) in various environments, the special viability and culturability of bioaerosols and their deposition doses in the respiratory system were evaluated. We conducted exposure assessments on inhalable aerosols in various indoor environments (childcare facilities, schools, commercial buildings, elderly and homes). The fractions of PM (PM, PM and PM) were investigated and, for the bioaerosol, the viability, culturability, inhalation daily dose and the deposited dose of the aerosol in the respiratory system were calculated to evaluate the human health effects. For two years, the distribution of the indoor PM concentration was high in all PM fractions in schools and commercial buildings, and low in the elderly and at homes. For airborne bacteria, the highest concentrations were shown in the childcare facility during the four seasons, while airborne fungi showed high concentrations in the buildings during the spring and summer, which showed significant differences from other investigated environments (between the buildings and elderly and homes: < 0.05). The viability and culturability for the bioaerosol showed no significant difference in all environments, and the correlation between inhalable PM and bioaerosol obtained from the six-stage impactor showed that the coefficient of determination (R) between coarse particles (PM, the size of stage 2-3) and cultivable airborne bacteria ranged from 0.70 (elderly and homes) to 0.84 (school) during the summer season.

摘要

由于空气质量差会对人类健康造成短期和长期影响,因此已经有大量研究针对室内和室外气溶胶暴露展开;然而,对于在人类生活的不同环境中含有生物气溶胶的可吸入气溶胶的暴露和健康风险,仍然缺乏具体的数据。为了研究不同环境中可吸入气溶胶(基于 R 模型的颗粒物监测(PM),PM 的变化取决于通风系统和基于大小分布的生物气溶胶)的潜在暴露情况,评估了生物气溶胶的特殊生存能力和可培养性及其在呼吸系统中的沉积剂量。我们对各种室内环境(儿童保育设施、学校、商业建筑、老年和家庭)中的可吸入气溶胶进行了暴露评估。研究了 PM 的分数(PM、PM 和 PM),并且对于生物气溶胶,计算了其生存能力、可培养性、每日吸入剂量和在呼吸系统中的气溶胶沉积剂量,以评估对人类健康的影响。在两年的时间里,所有 PM 分数的室内 PM 浓度分布在学校和商业建筑中都很高,而在老年和家庭中则较低。对于空气传播细菌,在四个季节中,儿童保育设施中的浓度最高,而空气传播真菌在春季和夏季的建筑物中浓度较高,这与其他调查环境(建筑物和老年和家庭之间:<0.05)有明显差异。在所有环境中,生物气溶胶的生存能力和可培养性均无显著差异,并且六级撞击器获得的可吸入 PM 与生物气溶胶之间的相关性表明,在夏季,粗颗粒(PM,第 2-3 级的大小)和可培养空气传播细菌之间的决定系数(R)范围从 0.70(老年和家庭)到 0.84(学校)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/5a1f7473bcc5/ijerph-17-01923-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/bfd2fc48294b/ijerph-17-01923-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/2d8ba2d44e39/ijerph-17-01923-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/8f90090855cf/ijerph-17-01923-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/f8e9f7723340/ijerph-17-01923-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/13d981c77712/ijerph-17-01923-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/9a0b4589a1d6/ijerph-17-01923-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/03dd852bec35/ijerph-17-01923-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/5a1f7473bcc5/ijerph-17-01923-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/bfd2fc48294b/ijerph-17-01923-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/2d8ba2d44e39/ijerph-17-01923-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/8f90090855cf/ijerph-17-01923-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/f8e9f7723340/ijerph-17-01923-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/13d981c77712/ijerph-17-01923-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/9a0b4589a1d6/ijerph-17-01923-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/03dd852bec35/ijerph-17-01923-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d93b/7142517/5a1f7473bcc5/ijerph-17-01923-g008.jpg

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