Department of Ophthalmology, Vejle Hospital, Vejle, Denmark.
Acta Ophthalmol. 2020 Sep;98(6):613-617. doi: 10.1111/aos.14408. Epub 2020 Mar 18.
To investigate the variance in keratometric (K) values after administration of different eye drops (three tested), and the effects on intraocular lens (IOL) power calculations in relation to standard cataract surgery.
A prospective intervention study (pilot study) on 38 participants (22 women, 16 men, 58-88 years) undergoing 57 cataract surgeries. Three keratometries on each eye were performed: a baseline ('standard') keratometry about 9 weeks preoperatively, and two on the operation day; a 'dry'-measurement before interventions and a 'wet'-measurement after applying one of three eye drops (saline, Systane Ultra , or Systane Complete ). All standard cataract operations were uneventful. Variabilities in K-values, spherical equivalents (SEQs) for IOL power calculations (Barrett TK Universal II) and subjective manifest refractions (SRs) 6 weeks postoperatively were compared between groups.
The 'wet' K-values had a similar variability to those of the 'standard' and 'dry' K-values (p > 0.05, anova on ranks). The mean paired differences in K-measurements between groups ranged within a small interval from -0.0107 to 0.0096 mm. After comparing the SEQ predictions with SR-measurements, the most precise IOL calculation was achieved after administration of a saline eye drop, but the precision was not statistically improved compared to the other drop modalities.
The variability in K-values was not significantly changed by administration of any of the different eye drops tested, suggesting that artificial eye drops do not impact the keratometry or IOL power prediction.
研究不同眼药水(三种测试眼药水)滴注后角膜曲率(K)值的变化,并评估其对标准白内障手术相关人工晶状体(IOL)度数计算的影响。
对 38 名(22 名女性,16 名男性,58-88 岁)接受 57 例白内障手术的患者进行前瞻性干预研究(初步研究)。每只眼进行 3 次角膜曲率测量:术前约 9 周进行“标准”角膜曲率测量,以及手术当天进行 2 次测量;干预前进行“干燥”测量,滴注三种眼药水(生理盐水、Systane Ultra 或 Systane Complete)后进行“湿润”测量。所有标准白内障手术均顺利进行。比较各组间 K 值、IOL 度数计算(Barrett TK Universal II)的球镜等效值(SEQ)和术后 6 周主观明视屈光度(SR)的变异性。
“湿润”K 值与“标准”和“干燥”K 值的变异性相似(p>0.05,秩和检验方差分析)。组间 K 测量值的平均配对差值在-0.0107 至 0.0096mm 的小范围内。将 SEQ 预测值与 SR 测量值进行比较后,发现滴注生理盐水后的 IOL 计算最精确,但与其他滴眼方式相比,精度无统计学改善。
滴注任何一种测试眼药水均不会显著改变 K 值的变异性,提示人工眼药水不会影响角膜曲率或 IOL 度数预测。