Stojanović Vesna D, Radovanović Tanja D, Koprivšek Katarina M, Vijatov Ðurić Gordana V, Doronjski Aleksandra D
Faculty of Medicine, Institute for Child and Youth Health Care of Vojvodina, Intermediate Care Unit, University of Novi Sad, Novi Sad, Serbia.
Faculty of Medicine, Institute for Child and Youth Health Care of Vojvodina, Intensive Care Unit, University of Novi Sad, Put Doktora Goldmana 4, Sremska Kamenica, Serbia.
Ann Indian Acad Neurol. 2020 Mar-Apr;23(2):228-232. doi: 10.4103/aian.AIAN_271_18. Epub 2020 Feb 25.
We report a case of a 7-year-old boy with Kawasaki disease (KD) complicated with cerebral vasculitis and encephalitis. The patient was admitted with signs of encephalopathy, seizures, and coma. The diagnosis of KD was made on the 2 day of hospitalization based on the clinical features (fever >5 days, maculopapular rash, nonpurulent conjunctivitis, fissured lips, and cervical adenopathy). Brain magnetic resonance imaging findings suggested cerebral vasculitis. Treatment with intravenous immunoglobulin was followed by mild improvement. After a single dose of immunoglobulin, pulse methylprednisolone therapy was started resulting in gradual improvement of consciousness and eventual complete motor and cognitive function recovery with regression of brain magnetic resonance lesions. KD can present with marked neurological symptomatology. Therefore, it should be considered in the differential diagnosis of encephalitis and encephalopathy etiologies in children.
我们报告一例7岁患川崎病（KD）并发脑血管炎和脑炎的男孩。该患者因脑病、癫痫发作和昏迷症状入院。根据临床特征（发热>5天、斑丘疹、非脓性结膜炎、唇裂和颈部淋巴结病），在住院第2天确诊为KD。脑磁共振成像结果提示脑血管炎。静脉注射免疫球蛋白治疗后稍有改善。单剂量免疫球蛋白治疗后，开始脉冲甲基强的松龙治疗，意识逐渐改善，最终运动和认知功能完全恢复，脑磁共振病变消退。KD可出现明显的神经症状。因此，在儿童脑炎和脑病病因的鉴别诊断中应考虑该病。
