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小唾液腺良性淋巴上皮病变——一种罕见的表现为腭部肿胀的疾病。

Benign lymphoepithelial lesion of the minor salivary gland - A rare presentation as a palatal swelling.

作者信息

Krithika Chandrasekaran, Sreedevi J, Sivapathasundharam B, Nithya V R

机构信息

Department of Oral Medicine and Radiology, Thai Moogambigai Dental College and Hospital, Chennai, Tamil Nadu, India.

Department of Oral Pathology, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India.

出版信息

J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S33-S36. doi: 10.4103/jomfp.JOMFP_17_20. Epub 2020 Feb 28.

DOI:10.4103/jomfp.JOMFP_17_20
PMID:32189901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7069127/
Abstract

Benign lymphoepithelial lesion (BLEL) is characterized by extensive lymphocytic infiltration of the major salivary glands and may be associated with Sjogren's syndrome or HIV infection. The involvement of the palatal minor salivary glands is extremely rare. We report an isolated case of BLEL affecting the palatal minor salivary glands, presenting as a palatal swelling in a 37-year-old female patient. Serological tests ruled out potential comorbid conditions. Cone-beam computed tomography showed a palatal soft-tissue mass with thinning of the adjacent cortical plates. A histopathological examination revealed salivary gland tissue with significant acinar destruction, dense lymphocytic infiltration and focal myoepithelial islands. Therefore, BLEL may be considered as a rare differential diagnostic possibility of a palatal soft-tissue mass lesion.

摘要

良性淋巴上皮病变（BLEL）的特征是主要唾液腺出现广泛的淋巴细胞浸润，可能与干燥综合征或HIV感染有关。腭部小唾液腺受累极为罕见。我们报告一例孤立的累及腭部小唾液腺的BLEL病例，表现为一名37岁女性患者的腭部肿胀。血清学检查排除了潜在的合并症。锥形束计算机断层扫描显示腭部软组织肿块，相邻皮质板变薄。组织病理学检查显示唾液腺组织有明显的腺泡破坏、密集的淋巴细胞浸润和局灶性肌上皮岛。因此，BLEL可被视为腭部软组织肿块病变一种罕见的鉴别诊断可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/58f44f4134e1/JOMFP-24-33-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/dee0681bd178/JOMFP-24-33-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/8e0636548f99/JOMFP-24-33-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/074bc5caeab9/JOMFP-24-33-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/ddc02fdd2e9c/JOMFP-24-33-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/fa0275bc9768/JOMFP-24-33-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/58f44f4134e1/JOMFP-24-33-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/dee0681bd178/JOMFP-24-33-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/8e0636548f99/JOMFP-24-33-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/074bc5caeab9/JOMFP-24-33-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/ddc02fdd2e9c/JOMFP-24-33-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/fa0275bc9768/JOMFP-24-33-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bca/7069127/58f44f4134e1/JOMFP-24-33-g006.jpg

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