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一名2日龄婴儿二度至三度烧伤的治疗:病例报告

Treatment of Second to Third-Degree Burns in A 2-Day-Old Infant: A Case Report.

作者信息

Ziegler Thomas, Cakl Thomas, Schauer Johannes, Pögl Dieter, Abdelkarim Ahmad, Kempny Tomas

机构信息

Division of Plastic and Reconstructive Surgery, Department of Surgery, Klinikum Wels-Grieskirchen, Austria.

出版信息

World J Plast Surg. 2020 Jan;9(1):82-87. doi: 10.29252/wjps.9.1.82.

DOI:10.29252/wjps.9.1.82
PMID:32190597
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7068179/
Abstract

Burn injuries in newborns are particularly complex cases. Since these patients are rare, there is little experience and no existing standardized treatment. This report examines a case of accidental second to third-degree burning of the heel and toes on the left foot in a new-born girl. The burns covered an estimated 1% of the total body surface area (TBSA). After an initial debridement and 32 days of non-surgical wound therapy with Adaptic® fat gauze dressings, we were able to achieve an aesthetically and functionally satisfactory result including the complete preservation of all toes. Modern wound treatment following the principle of less frequent dressing changes allows the burn wound to have better re-epithelialization. New findings in stem cell research indicate that the high proportion of mesenchymal stem cells (MSC) in postnatal blood is also involved in the regeneration and healing of burns. To our knowledge, this is the first case report dealing with initial non-surgical combustion therapy in a newborn. In order to eliminate a scar contracture, we carried out a Z-plasty one year later.

摘要

新生儿烧伤是特别复杂的病例。由于这类患者很罕见,几乎没有相关经验,也不存在现有的标准化治疗方法。本报告探讨了一名新生女婴左脚足跟和脚趾意外二度至三度烧伤的病例。烧伤面积估计占全身表面积(TBSA)的1%。在进行初步清创以及使用Adaptic®脂肪纱布敷料进行32天的非手术伤口治疗后,我们取得了美观和功能上令人满意的结果,包括所有脚趾均得以完整保留。遵循减少换药频率原则的现代伤口治疗方法能使烧伤创面实现更好的上皮再形成。干细胞研究的新发现表明,出生后血液中高比例的间充质干细胞(MSC)也参与烧伤的再生和愈合过程。据我们所知,这是第一例关于新生儿初始非手术烧伤治疗的病例报告。为了消除瘢痕挛缩,我们在一年后进行了Z成形术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b4b/7068179/83576742ae9c/wjps-9-82-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b4b/7068179/8587ddf8f109/wjps-9-82-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b4b/7068179/53f489aa4fe9/wjps-9-82-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b4b/7068179/83576742ae9c/wjps-9-82-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b4b/7068179/8587ddf8f109/wjps-9-82-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b4b/7068179/53f489aa4fe9/wjps-9-82-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b4b/7068179/83576742ae9c/wjps-9-82-g003.jpg

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本文引用的文献

1
The healing effect of Wharton's jelly stem cells seeded on biological scaffold in chronic skin ulcers: A randomized clinical trial.富含华通氏胶的干细胞在生物支架上对慢性皮肤溃疡的治疗效果:一项随机临床试验。
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Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulates rejuvenation of human skin.
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Novel View on Umbilical Cord Blood and Maternal Peripheral Blood-an Evidence for an Increase in the Number of Circulating Stem Cells on Both Sides of the Fetal-Maternal Circulation Barrier.关于脐血和母体外周血的新观点——胎儿-母体循环屏障两侧循环干细胞数量增加的证据。
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Thermal burn in a 30-minute-old newborn: report on the youngest patient with iatrogenic burn injury.30分钟大新生儿的热烧伤:关于最年轻医源性烧伤患者的报告。
Ann Burns Fire Disasters. 2017 Mar 31;30(1):62-64.
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A Prospective, Randomized, Controlled Trial Comparing the Outpatient Treatment of Pediatric and Adult Partial-Thickness Burns with Suprathel or Mepilex Ag.一项比较使用Suprathel或Mepilex Ag对儿童和成人浅二度烧伤进行门诊治疗的前瞻性、随机、对照试验
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The global burden of child burn injuries in light of country level economic development and income inequality.鉴于国家层面的经济发展和收入不平等情况,儿童烧伤伤害的全球负担。
Prev Med Rep. 2017 Mar 2;6:115-120. doi: 10.1016/j.pmedr.2017.02.024. eCollection 2017 Jun.
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Treatment of an acute deep hand burn in a lowincome country with no available microsurgery: a case report.在一个没有显微外科手术条件的低收入国家治疗急性手部深度烧伤:病例报告
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