Wahlund Tove, Jolstedt Maral, Andersson Erik, Vigerland Sarah, Perrin Sean, Öst Lars-Göran, Högström Jens, Serlachius Eva
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Solna, Sweden.
Stockholm Health Care Services, Stockholm County Council, CAP Research Centre, Stockholm, Sweden.
Mhealth. 2020 Jan 5;6:5. doi: 10.21037/mhealth.2019.09.10. eCollection 2020.
One in twenty adolescents experience excessive worry and evidence-based psychological therapies are not sufficiently widespread to reach most of those affected. In this multiple baseline evaluation, we assess the feasibility and preliminary efficacy of a scalable, online cognitive-behavioral intervention for adolescents with excessive worry (BIP worry).
Thirteen adolescents (age 13-17) with excessive worry underwent the 10-week online BIP worry intervention. The treatment also included an online intervention for parents. Completion rates, treatment satisfaction, and adverse events were measures of feasibility. Clinical outcomes included worry severity, symptoms of other anxiety and depression, and general functioning. To control for time and spontaneous fluctuations in symptoms, adolescents were randomized to a 2-, 6-, or 10-week baseline phase prior to treatment. A short measure of worry severity was administered weekly during the baseline and treatment phases. Outcomes were assessed before the baseline-phase, at pre-treatment, post-treatment, and at 1- and 3-month follow-ups.
Twelve of 13 included adolescents, together with their parents, participated in BIP worry, with a mean completion rate of 9.8 of the 10 treatment modules. Adolescents reported an average of 4.4 exposures per week as homework during treatment. High levels of treatment adherence, credibility, and satisfaction, and no serious adverse events were reported. Therapists averaged 21 min per week communicating with each family. Linear mixed effects models indicated significant improvements in worry, anxiety, and general functioning from pre- to post-treatment, with these gains maintained at 1- and 3-months follow-up. Reductions in worry severity during treatment were significantly larger than during the baseline phase. The results from the multiple baseline evaluation suggested an association between the introduction of the BIP worry intervention and subsequent symptom change for some but not all adolescents.
BIP worry is a feasible and potentially effective treatment. As the treatment is scalable and involves limited therapist contact, it represents a low-cost method for treating adolescents with excessive worry and anxiety. Further investigation under randomized controlled trial (RCT) conditions is warranted.
每二十名青少年中就有一人经历过度担忧,而循证心理疗法的普及程度不足以惠及大多数受影响的青少年。在这项多基线评估中,我们评估了一种针对过度担忧青少年(BIP担忧)的可扩展在线认知行为干预措施的可行性和初步疗效。
13名有过度担忧问题的青少年(年龄在13 - 17岁)接受了为期10周的在线BIP担忧干预。该治疗还包括针对家长的在线干预。完成率、治疗满意度和不良事件是可行性的衡量指标。临床结果包括担忧严重程度、其他焦虑和抑郁症状以及总体功能。为了控制时间和症状的自发波动,青少年在治疗前被随机分配到2周、6周或10周的基线期。在基线期和治疗期每周进行一次简短的担忧严重程度测量。在基线期之前、治疗前、治疗后以及1个月和3个月随访时评估结果。
13名纳入研究的青少年中有12名及其家长参与了BIP担忧干预,10个治疗模块的平均完成率为9.8。青少年在治疗期间作为家庭作业平均每周进行4.4次暴露练习。报告了高水平的治疗依从性、可信度和满意度,且未出现严重不良事件。治疗师平均每周与每个家庭沟通21分钟。线性混合效应模型表明,从治疗前到治疗后,担忧、焦虑和总体功能有显著改善,这些改善在1个月和3个月随访时得以维持。治疗期间担忧严重程度的降低显著大于基线期。多基线评估结果表明,对于部分但并非所有青少年而言,BIP担忧干预的引入与随后的症状变化之间存在关联。
BIP担忧干预是一种可行且可能有效的治疗方法。由于该治疗具有可扩展性且需要治疗师接触有限,它是治疗过度担忧和焦虑青少年的低成本方法。有必要在随机对照试验(RCT)条件下进行进一步研究。