University Radiology Unit, Radiology Department, Arcispedale Sant'Anna, Via A. Moro 8, Ferrara, 44123, Italy.
Department of Morphology, Surgery and Experimental Medicine, Radiology Section, University of Ferrara, Via L. Ariosto 35, Ferrara, 44121, Italy.
Med Oncol. 2020 Mar 19;37(4):31. doi: 10.1007/s12032-020-01355-z.
With increased use of medical imaging, the incidental detection of benign solid liver tumors has become more frequent. Facing with benign disease, the indications for surgery are still object of discussion in light of the stable natural course of most lesions and obvious drawbacks of any surgical intervention; therefore, in most situations, a conservative approach is recommended, and surgery is mainly reserved for those cases with persistent or worsening symptoms, or who are at risk for complications as malignant transformation. The advent of ablative techniques has widened the range of treatment options available to these patients, presenting as a valid alternative to resection in terms of safety and efficacy in selected cases, particularly in patients who are considered poor surgical candidates and with smaller lesions. This review outlines the role of percutaneous ablative methods for benign solid liver tumors that are encountered in adults, providing a per histology analysis of the existing evidence. The up-to-date strategies for management of the most common benign solid tumors are recapitulated.
随着医学影像学的广泛应用,良性实性肝脏肿瘤的偶然发现变得更加频繁。面对良性疾病,由于大多数病变的自然病程稳定,任何手术干预都存在明显的缺点,手术的适应证仍然存在争议;因此,在大多数情况下,建议采取保守方法,手术主要保留给那些持续或加重症状的患者,或有恶性转化并发症风险的患者。消融技术的出现拓宽了这些患者的治疗选择范围,在某些情况下,特别是在被认为是手术候选者较差和病变较小的患者中,其在安全性和疗效方面与切除术一样,成为一种有效的替代方法。本文回顾了经皮消融方法在成人良性实性肝脏肿瘤中的作用,按现有证据进行了组织学分析。总结了最常见的良性实性肿瘤的最新治疗策略。