Vošmik Milan, Hodek Miroslav, Buka David, Sýkorová Petra, Grepl Jakub, Paluska Petr, Paulíková Simona, Sirák Igor
Department of Oncology and Radiotherapy, University Hospital Hradec Kralove, Czech Republic.
Rep Pract Oncol Radiother. 2020 May-Jun;25(3):318-322. doi: 10.1016/j.rpor.2020.02.005. Epub 2020 Feb 25.
With a development of radiotherapeutic techniques, availability of radiotherapy data on cardiotoxicity, and slowly improving esophageal cancer outcomes, an increasing emphasis is placed on the heart protection in radiation treated esophageal cancer patients. Radiation induced heart complications encompass mainly pericardial disease, cardiomyopathy, coronary artery atherosclerosis, valvular heart disease, and arrhythmias. The most frequent toxicity is pericardial effusion which is usually asymptomatic in the majority of patients. The use of modern radiotherapy techniques is expected to reduce the risk of cardiotoxicity, although this expectation has to be confirmed by clinical data.
随着放射治疗技术的发展、心脏毒性放疗数据的可获取性以及食管癌治疗效果的缓慢改善，在接受放射治疗的食管癌患者中，心脏保护受到越来越多的重视。放射性心脏并发症主要包括心包疾病、心肌病、冠状动脉粥样硬化、心脏瓣膜病和心律失常。最常见的毒性反应是心包积液，大多数患者通常无症状。尽管这一期望有待临床数据证实，但使用现代放疗技术有望降低心脏毒性风险。
