Center for Health, Nutrition and Food, National Institute of Public Health in Prague, Palackeho 3a, CZ, 61242, Brno, Czech Republic; Department of Biology, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, CZ, 50003, Hradec Kralove, Czech Republic.
Center for Health, Nutrition and Food, National Institute of Public Health in Prague, Palackeho 3a, CZ, 61242, Brno, Czech Republic.
Food Chem Toxicol. 2020 May;139:111280. doi: 10.1016/j.fct.2020.111280. Epub 2020 Mar 18.
A dietary exposure assessment to sum of deoxynivalenol (DON) forms, sum of T-2/HT-2 toxins (T2/HT2) and zearalenone (ZEA) was conducted for Czech children 4-6 years and Czech men and women 18-59 years. Retail foods (25 different commodities, n = 336) were assessed by LC-MS/MS methods. The 95th percentile chronic exposure to sum of DON forms was determined in children from 648 to 1030 ng/kg bw/day (LB/lower bound/and UB/upper bound/), in men from 362 to 923 ng/kg bw/day and in women from 272 to 490 ng/kg bw/day. The 95th percentile chronic exposure to sum T2/HT2 was determined in children from 6.5 to 31 ng/kg bw/day, in men from 1.9 to 11.2 ng/kg bw/day and in women from 2.5 to 11.5 ng/kg bw/day. The 95th percentile chronic exposure to ZEA was determined in children from 11.9 to 24.9 ng/kg bw/day, in men from 5.9 to 27.5 ng/kg bw/day and in women from 4.8 to 12.6 ng/kg bw/day. The risk linked with the mean and the 95th percentile chronic exposure (LB scenario) to the sum of DON forms, sum of T2/HT2 and ZEA is considered to be out of health concern for the selected population groups.
对 4-6 岁的捷克儿童以及 18-59 岁的捷克男性和女性进行了脱氧雪腐镰刀菌烯醇（DON）、T-2/HT-2 毒素（T2/HT2）和玉米赤霉烯酮（ZEA）总量的膳食暴露评估。通过 LC-MS/MS 方法评估了零售食品（25 种不同商品，n=336）。确定了儿童、男性和女性对 DON 总量的 95%慢性暴露水平，分别为 648-1030ng/kg bw/day（LB/下限/和 UB/上限/）、362-923ng/kg bw/day 和 272-490ng/kg bw/day。儿童、男性和女性对 T2/HT2 总量的 95%慢性暴露水平分别为 6.5-31ng/kg bw/day、1.9-11.2ng/kg bw/day 和 2.5-11.5ng/kg bw/day。儿童、男性和女性对 ZEA 的 95%慢性暴露水平分别为 11.9-24.9ng/kg bw/day、5.9-27.5ng/kg bw/day 和 4.8-12.6ng/kg bw/day。基于平均和 95%慢性暴露（LB 情景）对 DON 总量、T2/HT2 总量和 ZEA 的风险评估被认为对所选人群群体的健康没有影响。
