Marie Curie Palliative Care Research Department, University College London, London, UK
School of Population Health & Environmental Sciences, King's College London, London, UK.
BMJ Support Palliat Care. 2020 Jun;10(2):209-212. doi: 10.1136/bmjspcare-2020-002224. Epub 2020 Mar 22.
Research suggests that clinicians are not very accurate at prognosticating in palliative care. The 'horizon effect' suggests that accuracy ought to be better when the survival of patients is shorter. The aim of this study was to determine the accuracy of specialist palliative care clinicians at identifying which patients are likely to die within 72 hours.
In a secondary data analysis of a prospective observational study, specialist palliative care doctors and nurses (in a hospice and a hospital palliative care team) provided survival predictions (yes/no/uncertain) about which patients would die within 72 hours.
Survival predictions were obtained for 49 patients. A prediction from a nurse was obtained for 37/49 patients. A prediction from a doctor was obtained for 46/49 patients. In total, 23 (47%)/49 patients actually died within 72 hours of assessment. Nurses accurately predicted the outcome in 27 (73%)/37 cases. Doctors accurately predicted the outcome in 30 (65%)/46 cases. When comparing predictions given on the same patients (27 [55%]/49), nurses were slightly better at recognising imminent death than doctors (positive predictive value (the proportion of patients who died when the clinician predicted death)=79% vs 60%, respectively). The difference in c-statistics (nurses 0.82 vs doctors 0.63) was not significant (p=0.13).
Even when patients are in the terminal phase and close to death, clinicians are not very good at predicting how much longer they will survive. Further research is warranted to improve prognostication in this population.
研究表明,临床医生在姑息治疗中的预后预测并不十分准确。“地平线效应”表明,当患者的生存时间较短时,准确性应该更高。本研究的目的是确定专科姑息治疗医生识别哪些患者可能在 72 小时内死亡的准确性。
在一项前瞻性观察研究的二次数据分析中,专科姑息治疗医生和护士(在临终关怀和医院姑息治疗团队中)对哪些患者将在 72 小时内死亡做出生存预测(是/否/不确定)。
为 49 名患者获得了生存预测。37/49 名患者获得了护士的预测。46/49 名患者获得了医生的预测。总共,23(47%)/49 名患者在评估后 72 小时内实际死亡。护士准确预测了 27(73%)/37 例的结果。医生准确预测了 30(65%)/46 例的结果。当比较对同一患者的预测(27 [55%]/49)时,护士在识别即将死亡方面略优于医生(阳性预测值(当医生预测死亡时死亡的患者比例)=79%比 60%)。C 统计量的差异(护士 0.82 比医生 0.63)无统计学意义(p=0.13)。
即使患者处于终末期并接近死亡,临床医生也不擅长预测他们还能存活多久。需要进一步研究以改善该人群的预后预测。