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运动肿瘤学研究重点的确定:一项共识研究

Identification of Research Priorities in Exercise Oncology: A Consensus Study.

作者信息

Morris Mhairi, Crank Helen, Loosemore Mike, Stevinson Clare

机构信息

School of Sport, Exercise and Health Sciences, Loughborough University, United Kingdom.

National Centre of Sport and Exercise Medicine East Midlands, United Kingdom.

出版信息

J Cancer. 2020 Feb 19;11(9):2702-2707. doi: 10.7150/jca.42992. eCollection 2020.

Abstract

The growth of research in the field of exercise oncology has resulted in a large evidence base for the role of physical activity in preventing and managing cancer outcomes. Nonetheless, there remain many unanswered questions across the multidisciplinary field. This study aimed to determine the priority research questions within exercise oncology using a systematic consensus method. Forty-seven exercise oncology experts engaged in the five-step process of the Nominal Group Technique to generate a list of research questions in small groups and rank the 10 most important. One hundred questions resulted from the process and fifteen received total scores (sum of ranks) of at least 50 from a maximum score of 470. The highest ranked question (score of 125) related to the identification of functional markers of recovery. The next five questions concerned minimum exercise parameters, health professional education, translation of behavioural interventions, effects of exercise on the tumour microenvironment and development of models to study the impact of exercise on cancer cell growth and metastasis. The study has demonstrated the importance of future research across all disciplinary areas of exercise oncology and identified the priority questions to which resources might be directed.

摘要

运动肿瘤学领域研究的发展为体育活动在预防和控制癌症结果方面的作用提供了大量证据。尽管如此,在这个多学科领域仍存在许多未解决的问题。本研究旨在使用系统的共识方法确定运动肿瘤学中的优先研究问题。47位运动肿瘤学专家参与了名义群体技术的五步流程,以小组形式生成研究问题列表,并对10个最重要的问题进行排名。该过程共产生了100个问题,其中15个问题的总分(排名总和)至少为50分(满分470分)。排名最高的问题(得分为125分)与恢复功能标志物的识别有关。接下来的五个问题涉及最低运动参数、卫生专业人员教育、行为干预的转化、运动对肿瘤微环境的影响以及研究运动对癌细胞生长和转移影响的模型开发。该研究证明了运动肿瘤学所有学科领域未来研究的重要性,并确定了可能分配资源的优先问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9094/7066012/61c9277e9d9d/jcav11p2702g001.jpg

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