University Politehnica of Bucharest, RO-060042 Bucharest, Romania.
University Politehnica of Bucharest, RO-060042 Bucharest, Romania.
Mater Sci Eng C Mater Biol Appl. 2020 May;110:110704. doi: 10.1016/j.msec.2020.110704. Epub 2020 Jan 28.
Taking into account the potential of barium titanate to deliver electrical stimulation to the physiological microenvironment and offer beneficial conditions for the cellular metabolism, this mineral phase was selected for the development of new composites. In this context, calcium phosphates and barium titanate were deposited on bacterial cellulose membranes under ultrasonic irradiation, the resulting system being subjected to a thermal treatment in optimized conditions in order to remove the polymeric template and achieve 3D porous architectures. The complex characterization performed on the intermediate and final samples demonstrated the suitability of such materials for hard tissue engineering applications.
考虑到钛酸钡将电刺激传递到生理微环境并为细胞代谢提供有益条件的潜力，选择这种矿物质相来开发新型复合材料。在此背景下，在超声辐射下将磷酸钙和钛酸钡沉积在细菌纤维素膜上，然后对所得系统进行热处理，在优化条件下去除聚合物模板，以实现 3D 多孔结构。对中间和最终样品进行的综合表征证明了这些材料适用于硬组织工程应用。
