Tuomilehto Jaakko, Ogle Graham D, Lund-Blix Nicolai A, Stene Lars C
Department of Public Health, University of Helsinki, Tukholmankatu 8B, PO Box 20, 00014 Helsinki, Finland, E-mail:
Life for a Child, Diabetes NSW, Sydney, Australia.
Pediatr Endocrinol Rev. 2020 Mar;17(Suppl 1):198-209. doi: 10.17458/per.vol17.2020.tol.epidemiologychildtype1diabetes.
Epidemiological data on pediatric type 1 diabetes (T1D), mainly incidence, have become increasingly available since the second half of the 20th century. Comparative incidence data across populations were only obtained since the 1980s. The 2019 IDF Atlas provides T1D incidence, prevalence and mortality estimates for children < 15 years for all 211 countries, but actual data were available for only 94 countries (only 3 low-income). The estimated prevalent cases were 600,900 and incident cases 98,200. Incidence remains highest in Finland (60/100,000/ year), Sardinia and Sweden, followed by Kuwait, some other northern European countries, Saudi Arabia, Algeria, Australia, New Zealand, USA and Canada. The lowest incidence is seen across East and South-East Asia. Globally, the average increase in incidence has been 3-4%/year over past decades, being steeper in low-incidence countries. Although T1D mortality has drastically decreased, there is still a higher risk compared with the non-diabetic population, especially in people with diabetic nephropathy.
自20世纪下半叶以来,有关儿童1型糖尿病(T1D)的流行病学数据,主要是发病率数据,越来越容易获取。自20世纪80年代起才获得不同人群间的发病率比较数据。《2019年国际糖尿病联合会地图集》提供了所有211个国家15岁以下儿童的T1D发病率、患病率和死亡率估计值,但仅有94个国家有实际数据(只有3个低收入国家)。估计的患病病例为600,900例,新发病例为98,200例。芬兰(每年60/10万)、撒丁岛和瑞典的发病率仍然最高,其次是科威特、其他一些北欧国家、沙特阿拉伯、阿尔及利亚、澳大利亚、新西兰、美国和加拿大。东亚和东南亚地区的发病率最低。在全球范围内,过去几十年发病率的平均年增长率为3%-4%,在低发病率国家增长更为明显。尽管T1D死亡率已大幅下降,但与非糖尿病患者群体相比,风险仍然较高,尤其是患有糖尿病肾病的患者。