Kimhy David, Lister Amanda, Liu Ying, Vakhrusheva Julia, Delespaul Philippe, Malaspina Dolores, Ospina Luz H, Mittal Vijay A, Gross James J, Wang Yuanjia
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
MIRECC, James J. Peters VA Medical Center, Bronx, NY, USA.
NPJ Schizophr. 2020 Mar 24;6(1):7. doi: 10.1038/s41537-020-0096-6.
Emotion regulation (ER) difficulties are ubiquitous among individuals with schizophrenia and have been hypothesized to contribute to stress sensitivity and exacerbation of psychotic symptoms in this population. However, the evidence supporting this link is equivocal, potentially due to previous studies' reliance on retrospective assessments of ER and psychosis, as well as lack of consideration of putative moderators such as emotion awareness. To address these limitations, we employed experience sampling method using mobile electronic devices to investigate the links between momentary in vivo use of ER strategies (ER), emotion awareness, and psychotic symptoms during daily functioning. Fifty-four individuals with schizophrenia completed assessment of ER and psychotic symptoms, along with traditional retrospective measures of ER and symptoms. Use of ER suppression predicted significant increases in momentary experiences of thought insertion, mind reading, auditory and visual hallucinations. Use of ER reappraisal predicted significant increases in momentary experiences of suspiciousness, thought insertion, and mind reading. Emotion awareness, driven primarily by difficulties identifying feelings, moderated the impact of ER on psychotic symptoms. There were no associations between retrospective measures of ER and symptoms. Our results indicate that, among individuals with schizophrenia, emotion awareness significantly impacts the relationship between use of ER and exacerbations in psychotic symptoms during the course of daily functioning. Our results highlight the need to incorporate emotion awareness and regulation difficulties into the development of treatment models and interventions for psychosis. In addition, our results underscore the need to employ in vivo, high time-resolution assessment methods to study dynamic clinical phenomena such as ER and psychotic symptoms.
情绪调节(ER)困难在精神分裂症患者中普遍存在,并且据推测这会导致该人群对应激敏感以及精神病症状加重。然而,支持这种关联的证据并不明确,这可能是由于先前的研究依赖于对情绪调节和精神病的回顾性评估,以及缺乏对诸如情绪意识等假定调节因素的考虑。为了解决这些局限性,我们采用移动电子设备的经验抽样法来研究日常功能中即时现场使用情绪调节策略(ER)、情绪意识和精神病症状之间的联系。54名精神分裂症患者完成了情绪调节和精神病症状的评估,以及情绪调节和症状的传统回顾性测量。使用情绪调节抑制预测了思维插入、读心术、听觉和视觉幻觉的即时体验显著增加。使用情绪调节重新评估预测了怀疑、思维插入和读心术的即时体验显著增加。主要由识别感觉困难驱动的情绪意识调节了情绪调节对精神病症状的影响。情绪调节的回顾性测量与症状之间没有关联。我们的结果表明,在精神分裂症患者中,情绪意识在日常功能过程中显著影响情绪调节的使用与精神病症状加重之间的关系。我们的结果强调了将情绪意识和调节困难纳入精神病治疗模型和干预措施开发的必要性。此外,我们的结果强调了采用现场、高时间分辨率评估方法来研究诸如情绪调节和精神病症状等动态临床现象的必要性。