关于Jamzad和Boiss对……影响的系统评价
A Systematic Review of the Effects of Jamzad and Boiss against .
作者信息
Khaledi Azad, Meskini Maryam
机构信息
Cellular and Molecular Gerash Research Center, Gerash University of Medical Sciences, Gerash, Iran.
Infectious Diseases Research Center, Department of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
出版信息
Iran J Med Sci. 2020 Mar;45(2):83-90. doi: 10.30476/IJMS.2019.72570..
BACKGROUND
The use of antibiotics is common, but its excessive or improper use leads to antibiotic resistance. Consequently, scientists have been interested in exploring traditional medicine to identify a new source of anti-bacterial agents. The present study aimed to conduct a systematic review to determine the anti-bacterial activity of Jamzad (SKJ) and Boiss (ZM) essential oils against in vitro.
METHODS
A comprehensive literature search for studies published on SKJ and ZM was carried out. Various keywords ( shirazi thyme, thymol, carvacrol; Iran, antibacterial effect; traditional medicine, phytomedicine, herbal medicine) were used to search both international and Iranian databases (Google Scholar, Science Direct, Web of Science, MEDLINE; PubMed, Scopus, Cochrane Library, Academic Search; Journal Storage, Magiran, Irandoc, Scientific Information Database (SID), and IranMedex). The selected articles were published during 2000-2017 and were written in English or Persian.
RESULTS
Seventeen articles were included in the review. The main ingredients of SKJ and ZM plants were carvacrol and thymol. The potential anti-bacterial activity of essential oils from these plants was confirmed. The carvacrol content, as the major active ingredient of SKJ was between 38.33-97.89%. The major ingredients of ZM were carvacrol (16.8-82.7%) followed by thymol (25.70-64.87%). The minimum inhibitory concentration () value of SKJ and ZM essential oils against bacterial strains was in the range of 0.31-450 and 2-8,000 μg/mL, respectively.
CONCLUSION
The present review study confirmed the anti-bacterial activity of SKJ and ZM, particularly against .
背景
抗生素的使用很普遍，但其过度或不当使用会导致抗生素耐药性。因此，科学家们一直对探索传统医学以寻找新的抗菌剂来源感兴趣。本研究旨在进行系统综述，以确定Jamzad（SKJ）和Boiss（ZM）精油的体外抗菌活性。
方法
对发表的关于SKJ和ZM的研究进行了全面的文献检索。使用了各种关键词（伊朗百里香、百里香酚、香芹酚；伊朗、抗菌作用；传统医学、植物医学、草药医学）在国际和伊朗数据库（谷歌学术、科学Direct、科学网、医学文献数据库；PubMed、Scopus、Cochrane图书馆、学术搜索；期刊存储库、Magiran、Irandoc、科学信息数据库（SID）和IranMedex）中进行搜索。所选文章发表于2000年至2017年期间，并用英语或波斯语撰写。
结果
该综述纳入了17篇文章。SKJ和ZM植物的主要成分是香芹酚和百里香酚。证实了这些植物精油具有潜在的抗菌活性。作为SKJ主要活性成分的香芹酚含量在38.33%-97.89%之间。ZM的主要成分是香芹酚（16.8%-82.7%），其次是百里香酚（25.70%-64.87%）。SKJ和ZM精油对细菌菌株的最低抑菌浓度（）值分别在0.31-450和2-8000μg/mL范围内。
结论
本综述研究证实了SKJ和ZM的抗菌活性，尤其是对 。
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