甲状腺髓样癌细针穿刺涂片可见多个奥氏小体：一项罕见发现。
Multiple Auer Rods in Fine-Needle Aspiration Smears of Medullary Thyroid Carcinoma: An Unusual Finding.
作者信息
Mohammadnia Avval Maryam, Kumar Perikala Vijayananda, Dehghani Fereydoon
机构信息
Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
Int Med Case Rep J. 2020 Mar 10;13:85-88. doi: 10.2147/IMCRJ.S244905. eCollection 2020.
BACKGROUND
Medullary thyroid carcinoma (MTC) is a rare tumor. Fine-needle aspiration (FNA) cytology is a popular method for the preoperative diagnosis of MTC.
CASE REPORT
A 45-year-old man was referred to our center for a palpable thyroid nodule. Ultrasound-guided FNA was carried out for the patient. Cytology slides showed many isolated and small clusters of round to oval cells, some with a moderate amount of cytoplasm and red cytoplasmic granules. Rare cells showed multiple red Auer rods. Histology confirmed the diagnosis of MTC.
CONCLUSION
Cytologic findings of MTC in FNA are variable, and several rare cytologic findings have been reported. Cytoplasmic red granules are one of the usual findings, whereas detection of cells containing multiple Auer rods is an unusual finding, which has not been reported so far.
背景
甲状腺髓样癌（MTC）是一种罕见的肿瘤。细针穿刺（FNA）细胞学检查是术前诊断MTC的常用方法。
病例报告
一名45岁男性因可触及的甲状腺结节被转诊至我院。对该患者进行了超声引导下FNA。细胞学涂片显示许多孤立的小群圆形至椭圆形细胞，部分细胞有中等量细胞质和红色细胞质颗粒。罕见细胞可见多条红色奥氏小体。组织学检查确诊为MTC。
结论
FNA检查中MTC的细胞学表现多样，已有多种罕见细胞学表现的报道。细胞质红色颗粒是常见表现之一，而检测到含有多条奥氏小体的细胞是一种不寻常的表现，目前尚未见报道。
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