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患银胶菊皮炎的生活痛苦:临床严重程度与生活质量的相关性。

Misery of Living with Parthenium Dermatitis: Correlation between Clinical Severity and Quality of Life.

作者信息

Agarwal Shail, Saini Shivani, Kumar Ramesh, Vijay Atul

机构信息

Department of Skin and VD, Jhalawar Medical College, Rajasthan, India.

Department of Skin and VD, Dr. SN. Medical College, Jodhpur, Rajasthan, India.

出版信息

Indian Dermatol Online J. 2021 Nov 22;12(6):860-863. doi: 10.4103/idoj.IDOJ_135_21. eCollection 2021 Nov-Dec.

Abstract

BACKGROUND

Parthenium dermatitis is caused by friable plant extracts of and related species. Approximately 40% of cases of plant dermatitis in India are contributed by this single species.

MATERIALS AND METHODS

This was a cross-sectional, observational study conducted in the Department of Dermatology of Jhalawar Medical College. Ninety-nine consecutive patch test positive human subjects of age more than 16 and either sex were included. The study period was 11 months between September 2019 and August 2020. Sociodemographic, clinical profile parthenium dermatitis severity score (PDSS) and Dermatology life quality index (DLQI) were obtained from each patient. Correlation between PDSS and DLQI was obtained using Pearson's two-tailed coefficients.

RESULTS

Our study included 62 men and 37 women (1.67:1). The mean age was 51 ± 10.27 years. Mean duration of disease was 8.47 ± 4.45 years, and mean PDSS was 57.25 ± 17.65, mean DLQI was 17.14 ± 5.56. ABCD with CAD was the most common clinical subtype (45.45%). A significant positive correlation was observed between PDSS and DLQI.

CONCLUSION

In this study, a significant impairment in quality of life (QoL) was observed in patients with higher score of PDSS and increasing duration, emphasizing that the disease needs specialized care including multiple indoor admission at the time of flare-up of disease.

摘要

背景

银胶菊皮炎由银胶菊及其相关物种的易碎植物提取物引起。在印度,约40%的植物性皮炎病例由该单一物种导致。

材料与方法

这是一项在贾拉瓦尔医学院皮肤科进行的横断面观察性研究。纳入了99名连续斑贴试验阳性、年龄超过16岁、性别不限的人类受试者。研究时间段为2019年9月至2020年8月的11个月。从每位患者处获取社会人口统计学、临床特征、银胶菊皮炎严重程度评分(PDSS)和皮肤病生活质量指数(DLQI)。使用Pearson双尾系数获得PDSS与DLQI之间的相关性。

结果

我们的研究纳入了62名男性和37名女性(比例为1.67:1)。平均年龄为51±10.27岁。疾病平均持续时间为8.47±4.45年,平均PDSS为57.25±17.65,平均DLQI为17.14±5.56。伴有CAD的ABCD是最常见的临床亚型(45.45%)。观察到PDSS与DLQI之间存在显著正相关。

结论

在本研究中,观察到PDSS评分较高且病程延长的患者生活质量(QoL)有显著损害,强调该疾病需要专门护理,包括在疾病发作时多次住院治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8213/8653731/50538894ae95/IDOJ-12-860-g001.jpg

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