艾灸对高蛋氨酸饮食诱导的高同型半胱氨酸血症和氧化应激的影响。
Effect of Moxibustion on Hyperhomocysteinemia and Oxidative Stress Induced by High-Methionine Diet.
作者信息
Wang Hao, Ha Lue, Hui Xin, Lin Yao, He Rui, Baixiao Zhao
机构信息
Beijing University of Chinese Medicine, Beijing, China.
出版信息
Evid Based Complement Alternat Med. 2020 Mar 9;2020:3184785. doi: 10.1155/2020/3184785. eCollection 2020.
OBJECTIVE
The aim of this study was to assess the effects of moxibustion on the animal model of oxidative stress and cardiovascular injury induced by high-methionine diet (2% methionine and 3.5% fat on the basis of ordinary maintenance feed) during 12 weeks.
METHODS
53 mice were divided into four groups: mice in the Control group ( = 8), mice in the Met group ( = 8), mice in the Met group ( = 8), mice in the Met group ( = 8), mice in the Met group (.
RESULTS
Compared with the Met group, our results indicated that through moxibustion intervention, the content of serum Hcy and its intermediate metabolite SAH can be reduced to a certain extent, and SOD, HO-1, and ox-LDL can be increased.
CONCLUSION
This study showed moxibustion's ability to enhance the body's antioxidation and protect vascular endothelial function, thus playing an early role in the prevention and treatment of atherosclerosis.
目的
本研究旨在评估艾灸对高蛋氨酸饮食（在普通维持饲料基础上含2%蛋氨酸和3.5%脂肪）诱导的氧化应激和心血管损伤动物模型在12周期间的影响。
方法
53只小鼠分为四组：对照组小鼠（n = 8），蛋氨酸组小鼠（n = 8），蛋氨酸组小鼠（n = 8），蛋氨酸组小鼠（n = 8），蛋氨酸组小鼠（.
结果
与蛋氨酸组相比，我们的结果表明，通过艾灸干预，血清同型半胱氨酸及其中间代谢产物S-腺苷同型半胱氨酸的含量可在一定程度上降低，超氧化物歧化酶、血红素加氧酶-1和氧化型低密度脂蛋白可增加。
结论
本研究表明艾灸具有增强机体抗氧化作用和保护血管内皮功能的能力，从而在动脉粥样硬化的防治中发挥早期作用。
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