The Cochrane Collaboration, St Albans House, Haymarket, St. James's, London.
Department of Advanced and Integrated Practice, School of Health and Social Care, London South Bank University, Borough Road, London, UK.
J Child Health Care. 2020 Jun;24(2):297-316. doi: 10.1177/1367493520914738. Epub 2020 Mar 27.
Congenital heart disease (CHD) is the most common birth defect. Little is known of the impact of having a sibling with CHD. Available literature documents negative impact of having a sibling with other chronic conditions. This literature review considers empirical evidence investigating the impact of having a sibling with CHD. Twelve databases were searched, and 202 articles retrieved. Eleven articles met the inclusion criteria and were subject to data extraction, quality appraisal, and narrative synthesis. Three themes emerged: changes in normal life, impact on siblings, and factors affecting the extent of impact on siblings. Only one intervention study was identified, 5 of 10 studies were conducted over 20 years ago, and only 4 studies included children as participants. Evidence suggests siblings of children with CHD experience adverse life changes which lead to negative impacts in several domains. Evidence is inconclusive regarding mitigating factors of these impacts. Further research is needed to understand the experiences of being a sibling of a child with CHD.
先天性心脏病（CHD）是最常见的出生缺陷。关于有一个患有 CHD 的兄弟姐妹的影响知之甚少。现有文献记录了患有其他慢性疾病的兄弟姐妹的负面影响。本文献综述考虑了调查有一个患有 CHD 的兄弟姐妹的影响的实证证据。搜索了 12 个数据库，共检索到 202 篇文章。11 篇文章符合纳入标准，并进行了数据提取、质量评估和叙述性综合分析。出现了三个主题：正常生活的变化、对兄弟姐妹的影响以及影响兄弟姐妹影响程度的因素。仅确定了一项干预研究，其中 10 项研究中有 5 项是在 20 年前进行的，只有 4 项研究将儿童作为参与者纳入其中。有证据表明，患有 CHD 儿童的兄弟姐妹经历了不利的生活变化，导致在几个领域产生负面影响。关于减轻这些影响的因素的证据尚无定论。需要进一步的研究来了解作为患有 CHD 的儿童的兄弟姐妹的经历。
