Department of Endocrinology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Graduate College, Beijing University of Traditional Chinese Medicine, Beijing, China.
BMJ Open Diabetes Res Care. 2020 Mar;8(1). doi: 10.1136/bmjdrc-2020-001181.
Metabolic syndrome (MetS) is a multifarious metabolic disorder that could severely damage multiple organs. The emergence of MetS has markedly increased medical burden for patients. The treatment of MetS involves multitarget regulation, which is the advantage of traditional Chinese medicine (TCM). Many high-quality studies related to TCM for MetS have been conducted in recent years; however, no overall efficacy analysis has been reported. To evaluate the efficacy and safety of TCM against MetS, we reviewed randomized controlled trials of MetS published in the past decade and then selected and analyzed 16 high-quality articles from over 800 papers. The results showed that TCM might be beneficial in improving body weight as well as in regulating glucose and lipid metabolisms; thus, TCM might be an ideal alternative therapy for MetS management. Treatment safety was also estimated in our analysis. A more elaborately designed and long-term observation of TCM for MetS should be performed in the future.
代谢综合征（MetS）是一种多种代谢紊乱的疾病，可严重损害多个器官。MetS 的出现显著增加了患者的医疗负担。MetS 的治疗涉及多靶点调节，这是中医药的优势。近年来，已经进行了许多与中医药治疗 MetS 相关的高质量研究，但尚未报道总体疗效分析。为了评估中医药治疗 MetS 的疗效和安全性，我们对过去十年发表的 MetS 随机对照试验进行了综述，然后从 800 多篇论文中选择并分析了 16 篇高质量文章。结果表明，中医药可能有助于改善体重以及调节血糖和脂质代谢；因此，中医药可能是 MetS 管理的一种理想替代疗法。我们的分析还评估了治疗安全性。未来应该进行更精心设计和长期观察中医药治疗 MetS。
