印度南部城市维洛尔的儿童中甲型肝炎爆发与伤寒和波诺感染同时发生。
Hepatitis A Outbreak with the Concurrence of Typhi and Poona Infection in Children of Urban Vellore, South India.
机构信息
Division of Gastrointestinal Sciences, Wellcome Trust Research Laboratory, Christian Medical College, Vellore, India.
Department of Community Health, Christian Medical College, Vellore, India.
出版信息
Am J Trop Med Hyg. 2020 Jun;102(6):1249-1252. doi: 10.4269/ajtmh.19-0742.
We investigated an outbreak of hepatitis A infection among children in an urban settlement of Vellore, South India. A total of 58 cases of jaundice were reported between April and August 2019. Sera from children who presented with jaundice were tested for hepatitis A virus (HAV) IgM. HAV IgM was positive in 18 (94.7%) of the 19 cases tested. These children also received a blood culture at the same time, as a part of the ongoing Surveillance for Enteric Fever in India (SEFI). Blood cultures from three children with confirmed hepatitis A infection grew sp: two with Typhi and one with Poona. Poona is being reported for the first time from India. The overall hospitalization rate during the outbreak was 21%. Outbreaks of hepatitis A continue to occur with substantial morbidity in children from endemic settings, with notable emergence of other concurrent enteric infections, thereby warranting continued surveillance.
我们调查了印度南部韦洛尔市一个城市住区的甲型肝炎感染暴发。2019 年 4 月至 8 月期间报告了 58 例黄疸病例。出现黄疸的儿童的血清均检测甲型肝炎病毒 (HAV) IgM。在检测的 19 例病例中，有 18 例（94.7%）HAV IgM 阳性。这些儿童还同时接受了血培养，这是印度肠热病监测（SEFI）的一部分。从 3 例确诊甲型肝炎感染的儿童的血液培养中培养出 sp：2 例伤寒和 1 例浦那。浦那首次在印度被报道。疫情期间的总体住院率为 21%。在流行地区，儿童的甲型肝炎暴发仍持续发生，发病率很高，同时出现其他并发的肠道感染，因此需要持续监测。
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