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综合虫媒病毒监测提高了巴拿马寨卡病毒的检出起始时间。

Integrated Arbovirus Surveillance Improves the Detection Onset of Zika Virus in Panama.

机构信息

Department of Biotechnology, Acharya Nagarjuna University, Guntur, India.

Instituto de Investigaciones Científicas y Servicios de Alta Tecnología, Panamá, República de Panamá.

出版信息

Am J Trop Med Hyg. 2020 May;102(5):985-987. doi: 10.4269/ajtmh.19-0316.

DOI:10.4269/ajtmh.19-0316
PMID:32228787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7204590/
Abstract

We tested 700 serum samples collected throughout Panama from 2015 to 2016 for detecting antibodies and RNA of arboviruses. In convalescent specimens, microsphere immunoassay detected an antibody prevalence of 59.3% for dengue virus (DENV) and 30.3% for Zika virus (ZIKV), which included samples that were collected before the Panamanian surveillance system reported the first case of Zika in the country. For acute sera, the most common arbovirus was DENV with 18 positive samples (6%), followed by four (1.3%) of ZIKV and one (0.6%) of chikungunya virus (CHIKV). Our results indicate a change in the chronology of when ZIKV was first detected in Panama and stress the importance of integrating various approaches to enable improved surveillance of both endemic and emerging arboviruses.

摘要

我们检测了 2015 年至 2016 年期间在巴拿马各地采集的 700 份血清样本,以检测虫媒病毒的抗体和 RNA。在恢复期标本中,微球免疫分析检测到登革热病毒 (DENV) 的抗体流行率为 59.3%,寨卡病毒 (ZIKV) 的抗体流行率为 30.3%,其中包括在巴拿马监测系统报告首例寨卡病毒病例之前采集的样本。对于急性血清,最常见的虫媒病毒是 DENV,有 18 个阳性样本 (6%),其次是 ZIKV 有 4 个阳性样本 (1.3%),基孔肯雅病毒 (CHIKV) 有 1 个阳性样本 (0.6%)。我们的结果表明,寨卡病毒在巴拿马首次被检测到的时间发生了变化,并强调了整合各种方法的重要性,以改善对地方性和新出现的虫媒病毒的监测。

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