Global Desalination Research Center (GDRC), School of Earth Sciences and Environmental Engineering, Gwangju Institute of Science and Technology (GIST), 123 Cheomdangwagi-ro, Buk-gu, Gwangju 61005, South Korea.
Global Desalination Research Center (GDRC), School of Earth Sciences and Environmental Engineering, Gwangju Institute of Science and Technology (GIST), 123 Cheomdangwagi-ro, Buk-gu, Gwangju 61005, South Korea; Chemical Engineering Department, Faculty of Engineering, Minia University, El-Minia, Egypt.
Mater Sci Eng C Mater Biol Appl. 2020 Apr;109:110596. doi: 10.1016/j.msec.2019.110596. Epub 2019 Dec 24.
The antimicrobial properties of two-dimensional materials such as graphene-based surfaces are vital for environmental and biomedical applications. Here, the improvement of the antibacterial property of reduced graphene oxide by the preparation of rGO-CuO nanocomposite films was reported. The rGO-CuO nanocomposites were synthesized via a simple hydrothermal method, and the nanocomposite films were fabricated by filtering through a polytetrafluoroethylene (PTFE) filter with the assistance of a vacuum filtration unit. After characterization of the nanocomposite films, the antibacterial properties were tested against Pseudomonas aeruginosa PAO1. The fabricated rGO-CuO nanocomposite films exhibited excellent antibacterial activity, leading to complete bacterial inactivation upon contact. The antibacterial properties were closely linked to the reactive oxygen species (ROS) independent pathway rather than the ROS-dependent pathway. This work provides an insight into the antibacterial mechanisms of reduced GO and copper oxide composite film for water treatment systems and the potential application of these nanocomposites in biomedicine.
二维材料（如基于石墨烯的表面）的抗菌性能对于环境和生物医学应用至关重要。在此，通过制备 rGO-CuO 纳米复合材料薄膜来提高还原氧化石墨烯的抗菌性能。rGO-CuO 纳米复合材料是通过简单的水热法合成的，纳米复合材料薄膜是通过在真空过滤单元的辅助下用聚四氟乙烯（PTFE）过滤器过滤来制备的。在对纳米复合材料薄膜进行表征后，测试了它们对铜绿假单胞菌 PAO1 的抗菌性能。所制备的 rGO-CuO 纳米复合材料薄膜表现出优异的抗菌活性，接触后可完全灭活细菌。抗菌性能与活性氧（ROS）非依赖性途径而非 ROS 依赖性途径密切相关。这项工作深入了解了还原 GO 和氧化铜复合薄膜在水处理系统中的抗菌机制，以及这些纳米复合材料在生物医学中的潜在应用。
