Fujikawa S, Hanawa Y, Ito H, Ohkuni M, Todome Y, Ohkuni H
Department of Pediatrics, Dokkyo Koshigaya Hospital, Japan.
Acta Otolaryngol Suppl. 1988;454:286-91. doi: 10.3109/00016488809125042.
The significance of antibody for streptolysin-O concerning tonsillectomy was studied. The results obtained were as follows. 1. The upper limit of ASO titer in 5,121 school children was 250 u and a value of more than 333 u was considered abnormal. But the level of the normal limit was different from year to year. 2. Among 143 cases with a high ASO titer of more than 833 u, only 12 cases had recurrent tonsillitis. There was no correlation between the tonsillar hypertrophy and the height of streptococcal antibodies. 3. There was a correlation between the titers determined by ELISA IgG-ASO and ASO in Todd units (r = 0.69), but there was no agreement between the titers determined by ELISA IgM-ASO and ASO in Todd units. 4. IgM-ASO determined by ELISA showed high levels in cases with early stages of streptococcal infection, focal infection and streptococcal carriers. Cases with high ASO, both IgG- and IgM-subclasses, were considered to have an indicative factor for tonsillectomy.
研究了抗链球菌溶血素O抗体在扁桃体切除术中的意义。所得结果如下。1. 5121名学童中抗链球菌溶血素O效价的上限为250单位，超过333单位的值被视为异常。但正常上限水平逐年不同。2. 在143例抗链球菌溶血素O效价高于833单位的病例中，只有12例有复发性扁桃体炎。扁桃体肥大与链球菌抗体水平之间没有相关性。3. 酶联免疫吸附测定法（ELISA）检测的IgG-抗链球菌溶血素O效价与托德单位（Todd units）的抗链球菌溶血素O效价之间存在相关性（r = 0.69），但酶联免疫吸附测定法检测的IgM-抗链球菌溶血素O效价与托德单位的抗链球菌溶血素O效价之间不一致。4. 酶联免疫吸附测定法检测的IgM-抗链球菌溶血素O在链球菌感染早期、局灶性感染和链球菌携带者的病例中显示出高水平。抗链球菌溶血素O（IgG和IgM亚类）水平高的病例被认为是扁桃体切除术的指征因素。
