Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha, Hunan 410013, China; Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, China.
Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha, Hunan 410013, China.
Int J Antimicrob Agents. 2020 May;55(5):105950. doi: 10.1016/j.ijantimicag.2020.105950. Epub 2020 Mar 29.
Viral respiratory diseases such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) always pose a severe threat to people. First identified in late December 2019, a novel coronavirus (2019-nCoV; SARS-CoV-2) has affected many provinces in China and multiple countries worldwide. The viral outbreak has aroused panic and a public-health emergency around the world, and the number of infections continues to rise. However, the causes and consequences of the pneumonia remain unknown. To effectively implement epidemic prevention, early identification and diagnosis are critical to disease control. Here we scrutinise a series of available studies by global scientists on the clinical manifestations, detection methods and treatment options for the disease caused by SARS-CoV-2, named coronavirus disease 2019 (COVID-19), and also propose potential strategies for preventing the infection.
病毒性呼吸道疾病，如严重急性呼吸综合征（SARS）和中东呼吸综合征（MERS），总是对人们构成严重威胁。一种新型冠状病毒（2019-nCoV；SARS-CoV-2）于 2019 年 12 月底首次被发现，已在中国多个省份和多个国家造成影响。病毒的爆发引起了全世界的恐慌和公共卫生紧急事件，感染人数持续上升。然而，肺炎的病因和后果仍不清楚。为了有效实施疫情防控，早期识别和诊断对疾病控制至关重要。在这里，我们仔细研究了全球科学家对由 SARS-CoV-2 引起的疾病（命名为 2019 年冠状病毒病（COVID-19））的临床表现、检测方法和治疗选择的一系列现有研究，并提出了预防感染的潜在策略。
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