Humanitas University, Via Rita Levi Montalcini, 4, 20090, Pieve Emanuele, MI, Italy.
Department of Otorhinolaryngology Head and Neck Surgery, IRCCS Humanitas Clinical and Research Center, Via Alessandro Manzoni, 56, 20089, Rozzano, MI, Italy.
Eur Arch Otorhinolaryngol. 2020 Jun;277(6):1837-1841. doi: 10.1007/s00405-020-05942-8. Epub 2020 Mar 31.
To analyze the surgical outcomes in terms of postoperative wound complications in a small case series of six patients treated with lateral cervical approach (LCA) for salvage total laryngectomy (STL) without prophylactic use of the pectoralis major myocutaneous flap (PMMF) or free flaps.
Between September 2018 and August 2019, six patients with recurrent/residual squamous-cell carcinoma after (chemo)radiotherapy [(C)RT] underwent STL with minimally invasive LCA with the anterior myocutaneous flap (AMCF), sparing the prelaryngeal tissue. Clinical records were retrospectively reviewed.
Wound dehiscence and local complications were prevented in five cases. Pharyngocutaneous fistula (PCF) occurred in one case and the closure was achieved by medical dressing with spontaneous healing within 15 days. Oral intake of liquids started 2 weeks after surgery in the five patients without local complications, after 24 days in the patient with PCF.
STL through the LCA after [(C)RT] failure seems to be feasible and effective in terms of prevention of local complications as wound dehiscence and fistula. More large clinical series are needed to confirm whether the use of LCA reduced the rate of postoperative wound complications following STL without the prophylactic use of pedicled or free flaps.
分析 6 例接受侧颈入路(LCA)挽救性全喉切除术(STL)的患者的术后伤口并发症的手术结果,这些患者在没有预防性使用胸大肌肌皮瓣(PMMF)或游离皮瓣的情况下接受了治疗。
2018 年 9 月至 2019 年 8 月,6 例接受(放)化疗后复发/残留鳞状细胞癌的患者接受了微创 LCA 联合前肌皮瓣(AMCF)的 STL,保留了咽前组织。回顾性分析临床记录。
5 例患者预防了伤口裂开和局部并发症。1 例患者发生咽皮瘘(PCF),经药物敷贴治疗,15 天内自发愈合。5 例无局部并发症的患者在术后 2 周开始经口摄入液体,PCF 患者在术后 24 天开始经口摄入液体。
在(放)化疗失败后,通过 LCA 行 STL 在预防伤口裂开和瘘管等局部并发症方面似乎是可行和有效的。需要更多的大样本临床系列研究来证实,在没有预防性使用带蒂或游离皮瓣的情况下,LCA 的使用是否降低了 STL 术后伤口并发症的发生率。