Branger Maxime, Loux Valentin, Cochard Thierry, Boschiroli Maria Laura, Biet Franck, Michelet Lorraine
INRAE, Université de Tours, ISP, 37380 Nouzilly, France.
Université Paris-Saclay, INRAE, MaIAGE, 78350, Jouy-en-Josas, France.
Infect Genet Evol. 2020 Aug;82:104309. doi: 10.1016/j.meegid.2020.104309. Epub 2020 Mar 30.
Mycobacterium bovis strain Mb3601 was isolated from the lymph node of an infected bovine in a bovine tuberculosis highly enzoonotic area of Burgundy, France. It was selected to obtain a complete genome for a new clonal complex, mainly constituted by SB0120-spoligotype strains that we propose to name "European 3". It was recently described as "clonal group I" based on whole-genome SNP analysis of 87 French strains. Here we describe the 4,365,068 bp complete genome obtained by the combination of PacBio and Illumina technologies. This genome of 65.64% G + C content includes 4024 predicted protein-coding genes, 52 tRNA, 3 rRNA and 11 copies of IS6110.
牛分枝杆菌菌株Mb3601是从法国勃艮第一个牛结核病高度地方流行区的一头受感染牛的淋巴结中分离出来的。它被选中用于获取一个新克隆复合体的完整基因组，该复合体主要由SB0120 - 寡核苷酸分型菌株组成，我们提议将其命名为“欧洲3型”。基于对87株法国菌株的全基因组单核苷酸多态性分析，它最近被描述为“克隆群I”。在此，我们描述了通过PacBio和Illumina技术相结合获得的4,365,068 bp完整基因组。这个G + C含量为65.64%的基因组包括4024个预测的蛋白质编码基因、52个tRNA、3个rRNA和11个IS6110拷贝。
