Department of Communication Sciences and Disorders, University of Iowa, Iowa City, IA 52242, United States.
Department of Psychiatry, The University of Iowa, The Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242, United States.
Brain Lang. 2020 Jun;205:104789. doi: 10.1016/j.bandl.2020.104789. Epub 2020 Mar 30.
The aim of the current study was to examine microstructural differences in white matter relevant to procedural and declarative memory between adolescents/young adults with and without Developmental Language Disorder (DLD) using diffusion tensor imaging (DTI). The findings showed atypical age-related changes in white matter structures in the corticostriatal system, in the corticocerebellar system, and in the medial temporal region in individuals with DLD. Results highlight the importance of considering the age factor in research on DLD. Future studies are needed to examine the developmental relationship between long-term memory and individual differences in language development and learning.
本研究旨在使用弥散张量成像(DTI)检查患有和不患有发育性语言障碍(DLD)的青少年/年轻人在与程序性和陈述性记忆相关的白质的微观结构差异。研究结果表明,DLD 个体的皮质纹状体系统、皮质小脑系统和内侧颞区的白质结构存在与年龄相关的异常变化。结果强调了在 DLD 研究中考虑年龄因素的重要性。需要进一步的研究来检查长期记忆与语言发展和学习中的个体差异之间的发展关系。