Croul-Ottman C E, Brunjes P C
Department of Psychology, University of Virginia, Charlottesville 22903.
Brain Res. 1988 Sep 20;460(2):323-8. doi: 10.1016/0006-8993(88)90376-9.
Littermate rat pups underwent either unilateral surgical occlusion of the right external naris or sham surgery on postnatal day 1. At 10, 20 or 30 days postpartum olfactory bulbs were sectioned and stained using nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) histochemistry. Two types of staining were observed and analyzed. The reaction produced a Golgi-like filling of short-axon cells in both deep and superficial bulb areas. No differences in the number, morphology or distribution of these cells were found either across ages or treatment conditions, indicating that the cells are resistant to the effects of the deprivation paradigm. Large regional variations in glomerular and olfactory nerve layer staining density were also observed at each age, reinforcing notions of functional or structural differences between glomeruli at very early ages.
同窝出生的大鼠幼崽在出生后第1天接受了右侧外鼻孔单侧手术闭塞或假手术。在产后10、20或30天，对嗅球进行切片，并使用烟酰胺腺嘌呤二核苷酸磷酸黄递酶（NADPH-d）组织化学进行染色。观察并分析了两种染色类型。该反应在嗅球深部和浅部区域产生了类似高尔基氏染色的短轴突细胞填充。在不同年龄或处理条件下，这些细胞的数量、形态或分布均未发现差异，这表明这些细胞对剥夺模式的影响具有抗性。在每个年龄，还观察到肾小球和嗅神经层染色密度存在较大的区域差异，这强化了在非常早期肾小球之间功能或结构差异的观念。
