一起与 2019 年新型冠状病毒相关的家族聚集性感染提示在潜伏期可能存在人际传播。
A Familial Cluster of Infection Associated With the 2019 Novel Coronavirus Indicating Possible Person-to-Person Transmission During the Incubation Period.
机构信息
Jingan District Center for Disease Control and Prevention, Shanghai, China.
Shanghai Center for Disease Control and Prevention, Shanghai, China.
出版信息
J Infect Dis. 2020 May 11;221(11):1757-1761. doi: 10.1093/infdis/jiaa077.
Abstract
An ongoing outbreak of pneumonia associated with 2019 novel coronavirus was reported in China. It is unclear whether the virus is infective exists during the incubation period, although person-to-person transmission has been reported elsewhere. We report the epidemiological features of a familial cluster of 4 patients in Shanghai, including an 88-year-old man with limited mobility who was exposed only to asymptomatic family members whose symptoms developed later. The epidemiological evidence has shown possible transmission of 2019 novel coronavirus during the incubation period.
摘要
中国报告了一起与 2019 年新型冠状病毒相关的肺炎疫情爆发。目前尚不清楚该病毒在潜伏期是否具有传染性，尽管其他地方已经报告了人际传播的情况。我们报告了上海一家族性聚集性病例的流行病学特征，包括一名 88 岁行动受限的男子，他仅接触过后来出现症状的无症状家庭成员。流行病学证据表明，2019 年新型冠状病毒在潜伏期可能具有传染性。
相似文献
1
A Familial Cluster of Infection Associated With the 2019 Novel Coronavirus Indicating Possible Person-to-Person Transmission During the Incubation Period.一起与 2019 年新型冠状病毒相关的家族聚集性感染提示在潜伏期可能存在人际传播。
J Infect Dis. 2020 May 11;221(11):1757-1761. doi: 10.1093/infdis/jiaa077.
2
Rapid asymptomatic transmission of COVID-19 during the incubation period demonstrating strong infectivity in a cluster of youngsters aged 16-23 years outside Wuhan and characteristics of young patients with COVID-19: A prospective contact-tracing study.在潜伏期内 COVID-19 无症状快速传播，在武汉以外的一群年龄在 16-23 岁的年轻人中表现出很强的传染性，以及 COVID-19 年轻患者的特点：一项前瞻性接触者追踪研究。
J Infect. 2020 Jun;80(6):e1-e13. doi: 10.1016/j.jinf.2020.03.006. Epub 2020 Apr 10.
3
A Family Cluster of Coronavirus Disease (COVID-19) Infection with Different Clinical Manifestations.一个具有不同临床表现的新型冠状病毒肺炎（COVID-19）感染家庭聚集性病例
Acta Med Indones. 2020 Apr;52(2):155-162.
4
Nosocomial outbreak of COVID-19 pneumonia in Wuhan, China.中国武汉发生的 COVID-19 肺炎医院感染暴发。
Eur Respir J. 2020 Jun 4;55(6). doi: 10.1183/13993003.00544-2020. Print 2020 Jun.
5
[Epidemiological analysis on a family cluster of COVID-19].新型冠状病毒肺炎家庭聚集性的流行病学分析
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Apr 10;41(4):494-497. doi: 10.3760/cma.j.cn112338-20200221-00147.
6
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.一个涉及 2019 年新型冠状病毒的家庭聚集性肺炎病例，提示存在人际传播：一项家庭聚集性研究。
Lancet. 2020 Feb 15;395(10223):514-523. doi: 10.1016/S0140-6736(20)30154-9. Epub 2020 Jan 24.
7
The Novel Coronavirus: A Bird's Eye View.新型冠状病毒：概览
Int J Occup Environ Med. 2020 Apr;11(2):65-71. doi: 10.15171/ijoem.2020.1921. Epub 2020 Feb 5.
8
Epidemiological Characteristics and Incubation Period of 7015 Confirmed Cases With Coronavirus Disease 2019 Outside Hubei Province in China.中国湖北省外 7015 例新型冠状病毒病确诊病例的流行病学特征和潜伏期。
J Infect Dis. 2020 Jun 16;222(1):26-33. doi: 10.1093/infdis/jiaa211.
9
Indirect Virus Transmission in Cluster of COVID-19 Cases, Wenzhou, China, 2020.2020 年中国温州新冠肺炎聚集性疫情中的间接病毒传播。
Emerg Infect Dis. 2020 Jun;26(6):1343-1345. doi: 10.3201/eid2606.200412. Epub 2020 Jun 17.
10
Coronavirus in China.中国的冠状病毒。
Lancet Respir Med. 2020 Mar;8(3):238. doi: 10.1016/S2213-2600(20)30056-4. Epub 2020 Feb 3.
引用本文的文献
1
Identification of the high-risk residence communities and possible risk factors of COVID-19 in Wuhan, China.中国武汉新冠病毒肺炎高风险居住社区及潜在风险因素的识别
J Saf Sci Resil. 2021 Jun;2(2):31-39. doi: 10.1016/j.jnlssr.2021.04.001. Epub 2021 Apr 24.
2
Could Anemia Impact the Severity of Infections? COVID-19 as an Example.贫血会影响感染的严重程度吗？以新冠病毒为例。
F1000Res. 2024 Nov 5;13:295. doi: 10.12688/f1000research.144790.2. eCollection 2024.
3
Clinical and epidemiological profiles of pediatric COVID-19 in two private Kenyan hospitals.肯尼亚两家私立医院儿童新冠肺炎的临床和流行病学概况
Pan Afr Med J. 2024 Jun 7;48:48. doi: 10.11604/pamj.2024.48.48.39305. eCollection 2024.
4
SARS-CoV-2 RNA Detection in Wastewater and Its Effective Correlation with Clinical Data during the Outbreak of COVID-19 in Salamanca.SARS-CoV-2 RNA 在废水中的检测及其与 COVID-19 爆发期间萨拉曼卡临床数据的有效关联。
Int J Mol Sci. 2024 Jul 24;25(15):8071. doi: 10.3390/ijms25158071.
5
The comparison of decay rates of infectious SARS-CoV-2 and viral RNA in environmental waters and wastewater.环境水体和废水中传染性 SARS-CoV-2 和病毒 RNA 衰减率的比较。
Sci Total Environ. 2024 Oct 10;946:174379. doi: 10.1016/j.scitotenv.2024.174379. Epub 2024 Jun 30.
6
Tied Infections: How Social Connectedness to Other COVID-19 Patients Influences Illness Severity.关联感染：与其他新冠患者的社会联系如何影响疾病严重程度
Am Behav Sci. 2021 Dec;65(14):1901-1928. doi: 10.1177/00027642211003138.
7
Transportation as a Disease Vector in COVID-19: Border Mobility and Disease Spread.交通运输作为新冠疫情中的疾病传播媒介：边境流动性与疾病传播
Transp Res Rec. 2023 Apr;2677(4):826-838. doi: 10.1177/03611981231156588. Epub 2023 Mar 10.
8
Workplace interventions to reduce the risk of SARS-CoV-2 infection outside of healthcare settings.工作场所干预措施以降低医疗机构外 SARS-CoV-2 感染的风险。
Cochrane Database Syst Rev. 2024 Apr 10;4(4):CD015112. doi: 10.1002/14651858.CD015112.pub3.
9
Mitigating the COVID-19 Pandemic through Data-Driven Resource Sharing.通过数据驱动的资源共享缓解新冠疫情。
Nav Res Logist. 2024 Feb;71(1):41-63. doi: 10.1002/nav.22117. Epub 2023 Apr 29.
10
Post-COVID-19 Illness Trend in a Local Community in Bangladesh.孟加拉国一个当地社区的新冠后疾病趋势
Cureus. 2023 Sep 26;15(9):e45998. doi: 10.7759/cureus.45998. eCollection 2023 Sep.
本文引用的文献
1
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.新型冠状病毒感染肺炎在中国武汉的早期传播动力学。
N Engl J Med. 2020 Mar 26;382(13):1199-1207. doi: 10.1056/NEJMoa2001316. Epub 2020 Jan 29.
2
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.中国武汉地区 2019 年新型冠状病毒感染患者的临床特征。
Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
3
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.一个涉及 2019 年新型冠状病毒的家庭聚集性肺炎病例，提示存在人际传播：一项家庭聚集性研究。
Lancet. 2020 Feb 15;395(10223):514-523. doi: 10.1016/S0140-6736(20)30154-9. Epub 2020 Jan 24.
4
A novel coronavirus outbreak of global health concern.一场引发全球卫生关注的新型冠状病毒疫情。
Lancet. 2020 Feb 15;395(10223):470-473. doi: 10.1016/S0140-6736(20)30185-9. Epub 2020 Jan 24.
5
A Novel Coronavirus from Patients with Pneumonia in China, 2019.2019 年中国肺炎患者中的一种新型冠状病毒。
N Engl J Med. 2020 Feb 20;382(8):727-733. doi: 10.1056/NEJMoa2001017. Epub 2020 Jan 24.
6
Saliva as a diagnostic specimen for testing respiratory virus by a point-of-care molecular assay: a diagnostic validity study.即时分子检测法以唾液为标本检测呼吸道病毒的诊断准确性研究。
Clin Microbiol Infect. 2019 Mar;25(3):372-378. doi: 10.1016/j.cmi.2018.06.009. Epub 2018 Jun 12.
7
Middle East respiratory syndrome coronavirus: risk factors and determinants of primary, household, and nosocomial transmission.中东呼吸综合征冠状病毒：原发性、家庭和医院传播的风险因素和决定因素。
Lancet Infect Dis. 2018 Aug;18(8):e217-e227. doi: 10.1016/S1473-3099(18)30127-0. Epub 2018 Apr 18.
8
Infectivity of severe acute respiratory syndrome during its incubation period.严重急性呼吸综合征潜伏期的传染性。
Biomed Environ Sci. 2009 Dec;22(6):502-10. doi: 10.1016/S0895-3988(10)60008-6.
9
Viral load in patients infected with pandemic H1N1 2009 influenza A virus.感染 2009 年甲型 H1N1 流感病毒患者的病毒载量。
J Med Virol. 2010 Jan;82(1):1-7. doi: 10.1002/jmv.21664.
10
Viral shedding patterns of coronavirus in patients with probable severe acute respiratory syndrome.疑似严重急性呼吸综合征患者中冠状病毒的病毒脱落模式
Lancet. 2004 May 22;363(9422):1699-700. doi: 10.1016/S0140-6736(04)16255-7.
Zotero 插件